Perioperative central venous oxygen saturation and its correlation with mortality during cardiac surgery: an observational prospective study

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorDisciplina de Anestesiologia-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorFaculdade de Medicina de Jundiaí-
Autor(es): dc.creatorMiranda, César de Araujo-
Autor(es): dc.creatorMeletti, José F.A.-
Autor(es): dc.creatorLima, Laís H.N. [UNESP]-
Autor(es): dc.creatorMarchi, Evaldo-
Data de aceite: dc.date.accessioned2022-02-22T00:32:13Z-
Data de disponibilização: dc.date.available2022-02-22T00:32:13Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.bjan.2020.04.014-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200962-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200962-
Descrição: dc.descriptionBackground: Cardiac surgery can produce persistent deficit in the ratio of Oxygen Delivery (DO2) to Oxygen Consumption (VO2). Central venous oxygen Saturation (ScvO2) is an accessible and indirect measure of DO2/VO2 ratio. Objective: To monitor perioperative ScvO2 and assess its correlation with mortality during cardiac surgery. Methods: This prospective observational study evaluated 273 patients undergoing cardiac surgery. Blood gas samples were collected to measure ScvO2 at three time points: T0 (after anesthetic induction), T1 (end of surgery), and T2 (24 hours after surgery). The patients were divided into two groups (survivors and nonsurvivors). The following outcomes were analyzed: intrahospital mortality, length of Intensive Care Unit (ICU) and hospital stay (LOS), and variation in ScvO2. Results: Of the 273 patients, 251 (92%) survived and 22 (8%) did not. There was a significant perioperative reduction of ScvO2 in both survivors (T0 = 78% ± 8.1%, T1 = 75.4% ± 7.5%, and T2 = 68.5% ± 9%; p < 0.001) and nonsurvivors (T0 = 74.4% ± 8.7%, T1 = 75.4% ± 7.7%, and T2 = 66.7% ± 13.1%; p < 0.001). At T0, the percentage of patients with ScvO2 < 70% was greater in the nonsurvivor group (31.8% vs. 13.1%; p = 0.046) and the multiple logistic regression showed that ScvO2 is an independent risk factor associated with death, OR = 2.94 (95% CI 1.10 − 7.89) (p = 0.032). The length of ICU and LOS were 3.6 ± 3.1 and 7.4 ± 6.0 days respectively and was not significantly associated with ScvO2. Conclusions: Early intraoperative ScvO2 < 70% indicated a higher risk of death. A perioperative reduction of ScvO2 was observed in patients undergoing cardiac surgery, with high intraoperative and lower postoperative levels.-
Descrição: dc.descriptionFaculdade de Medicina de Jundiaí Disciplina de Anestesiologia-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Medicina de Botucatu Departamento de Anestesiologia-
Descrição: dc.descriptionFaculdade de Medicina de Jundiaí-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Medicina de Botucatu Departamento de Anestesiologia-
Idioma: dc.languageen-
Idioma: dc.languagept_BR-
Relação: dc.relationBrazilian Journal of Anesthesiology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBlood gas analyses-
Palavras-chave: dc.subjectCardiac surgery procedures-
Palavras-chave: dc.subjectMortality-
Palavras-chave: dc.subjectPerioperative care-
Palavras-chave: dc.subjectVenous catheterization-
Título: dc.titlePerioperative central venous oxygen saturation and its correlation with mortality during cardiac surgery: an observational prospective study-
Título: dc.titleCorrelação entre saturação venosa central de oxigênio perioperatória e mortalidade em cirurgia cardíaca: estudo prospectivo observacional-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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