Oxidative stress monitoring in in vitro and in vivo models

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorCenter for Evaluation of Environmental Impact on Human Health (TOXICAM)-
Autor(es): dc.creatorLima, Thania Rios Rossi [UNESP]-
Autor(es): dc.creatorSales, Bianca Camargo Penteado [UNESP]-
Autor(es): dc.creatorPereira, Lilian Cristina [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:32:06Z-
Data de disponibilização: dc.date.available2022-02-22T00:32:06Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/978-981-15-1568-2_10-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200925-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200925-
Descrição: dc.descriptionIn aerobic organisms, cellular respiration is an essential process that is divided into several steps. The third and last step is called oxidative phosphorylation, which occurs in the mitochondria, specifically in the inner mitochondrial membrane. The mitochondria are considered the cell “powerhouse” because they generate energy through oxidative phosphorylation, which is the main energy source in aerobic organisms. The generated energy is stored in the ATP molecule and is used to maintain various biological processes. Conversely, the mitochondria are also the primary site for reactive oxygen species (ROS) production. If ROS are produced beyond the capacity of antioxidant systems to neutralize them, they induce oxidative stress. This condition is harmful for macromolecules and can lead to cell death. Oxidative stress and its consequences can be monitored by many assays that employ in vitro and in vivo models, which will be discussed throughout this chapter.-
Descrição: dc.descriptionDepartment of Pathology Botucatu Medical School São Paulo State University (UNESP)-
Descrição: dc.descriptionCenter for Evaluation of Environmental Impact on Human Health (TOXICAM)-
Descrição: dc.descriptionFaculty of Agronomic Sciences of Botucatu Department of Bioprocesses and Biotechnology São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Pathology Botucatu Medical School São Paulo State University (UNESP)-
Descrição: dc.descriptionFaculty of Agronomic Sciences of Botucatu Department of Bioprocesses and Biotechnology São Paulo State University (UNESP)-
Formato: dc.format163-178-
Idioma: dc.languageen-
Relação: dc.relationRole of Oxidative Stress in Pathophysiology of Diseases-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCellular culture-
Palavras-chave: dc.subjectOxidative stress monitoring-
Palavras-chave: dc.subjectROS-
Palavras-chave: dc.subjectZebrafish-
Título: dc.titleOxidative stress monitoring in in vitro and in vivo models-
Aparece nas coleções:Repositório Institucional - Unesp

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