Preliminary survey of the attitudes of Brazilian scientists towards pain management and assessment in animals used in science

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Estadual de Maringá (UEM)-
Autor(es): dc.contributorUniversidade Federal de Lavras (UFLA)-
Autor(es): dc.creatorTomacheuski, Rubia M. [UNESP]-
Autor(es): dc.creatorTaffarel, Marilda O.-
Autor(es): dc.creatorFerrante, Marcos-
Autor(es): dc.creatorLuna, Stelio PL. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:31:40Z-
Data de disponibilização: dc.date.available2022-02-22T00:31:40Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-09-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.vaa.2020.05.007-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200771-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200771-
Descrição: dc.descriptionObjective: To investigate the current scenario in Brazil regarding pain assessment and control in experimental animals. Study design: Prospective survey. Methods: A confidential questionnaire was available online and sent by e-mail to Brazilian scientists working with animal experimentation in Brazil. Data collection was conducted from October 2016 to October 2017. The exclusion criteria included blank questionnaires or with <80% completed responses, researchers not performing experiments involving animals and foreign scientists. Results: A total of 96 questionnaires from 104 respondents were analyzed. The Fisher's exact test showed a disparity between the proportions of scientists who recognized the importance of analgesia and their application of analgesic techniques in painful procedures (p < 0.0003), and also for the researchers who assumed that experiments inflicted pain and their classification of the degree of invasiveness (p < 0.0001), indicating their insufficient knowledge of these topics. Overall, 77% of institutions did not offer specific training to assess pain in experimental animals, and 24% of respondents had no training to work with animal experimentation. In total, 62% of the studies inflicted pain, 48% of respondents used pain scales, and the drugs administered most frequently for pain management were morphine (44%), meloxicam (43%) and tramadol (37%); 15% of respondents did not include analgesics even though their studies inflicted pain. Commonly used animals were rats (33%), mice (29%) and rabbits (8%). Conclusions and clinical relevance: The results of this preliminary survey indicated that in Brazil there is a gap in the knowledge and training on pain assessment and management of experimental animals. Therefore, there is a necessity for an educational program to prepare and train scientists to assess and manage pain in laboratory or experimental animals. Further studies using a psychometrically validated survey instrument are warranted.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Anesthesiology Medical School (FMB) of São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Veterinary Medicine Maringá State University (UEM)-
Descrição: dc.descriptionDepartment of Veterinary Medicine Federal University of Lavras (UFLA)-
Descrição: dc.descriptionDepartment of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Anesthesiology Medical School (FMB) of São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science São Paulo State University (UNESP)-
Descrição: dc.descriptionFAPESP: 2017/12815-0-
Formato: dc.format647-656-
Idioma: dc.languageen-
Relação: dc.relationVeterinary Anaesthesia and Analgesia-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectanalgesia-
Palavras-chave: dc.subjectanalgesics-
Palavras-chave: dc.subjectlaboratory animals-
Palavras-chave: dc.subjectpain measurement-
Palavras-chave: dc.subjectrats-
Palavras-chave: dc.subjectsurvey-
Título: dc.titlePreliminary survey of the attitudes of Brazilian scientists towards pain management and assessment in animals used in science-
Tipo de arquivo: dc.typelivro digital-
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