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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | University of Sagrado Coracao | - |
Autor(es): dc.creator | Grossi-Oliveira, Gustavo [UNESP] | - |
Autor(es): dc.creator | Faverani, Leonardo P. [UNESP] | - |
Autor(es): dc.creator | Mendes, Bruno Coelho [UNESP] | - |
Autor(es): dc.creator | Braga Polo, Tárik Ocon [UNESP] | - |
Autor(es): dc.creator | Batista Mendes, Gabriel Cury | - |
Autor(es): dc.creator | Lima, Valthierre Nunes De [UNESP] | - |
Autor(es): dc.creator | Ribeiro Júnior, Paulo Domingos | - |
Autor(es): dc.creator | Okamoto, Roberta [UNESP] | - |
Autor(es): dc.creator | Magro-Filho, Osvaldo [UNESP] | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:31:04Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:31:04Z | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2019-12-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1155/2020/5182845 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/200564 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/200564 | - |
Descrição: dc.description | This study evaluated the osteoconductive potential of four biomaterials used to fill bone defects. For this, 24 male Albino rabbits were submitted to the creation of a bilateral 8 mm calvarial bone defect. The animals were divided into four groups - bovine hydroxyapatite, Bio-Oss® (BIO); Lumina-Bone Porous® (LBP); Bonefill® (BFL); and an alloplastic material, Clonos® (CLN) - and were euthanized at 14 and 40 days. The samples were subjected to histological and histometric analysis for newly formed bone area. Immunohistochemical analysis for Runt-related transcription factor 2 (Runx2), vascular endothelial growth factor (VEGF), and osteocalcin (OC) was performed. After statistical analysis, the CLN group showed greater new bone formation (NB) in both periods analyzed (p<0.05). At 14 days, the NB showed greater values in BIO in relation to LBP and BFL groups; however, after 40 days, the LBP group surpassed the results of BIO (p<0.001). The immunostaining showed a decrease in Runx2 intensity in BIO after 40 days, while it increased for LBP (p<0.05). The CLN showed increased OC compared to the other groups in both periods analyzed (p<0.05). Therefore, CLN showed the best osteoconductive behavior in critical defects in rabbit calvaria, and BFL showed the lowest osteoconductive property. | - |
Descrição: dc.description | Oral and Maxillofacial Surgery Diagnostic and Surgery Aracatuba School of Dentistry Sao Paulo State University (UNESP) | - |
Descrição: dc.description | Oral and Maxillofacial Surgery Department of Oral Surgery University of Sagrado Coracao | - |
Descrição: dc.description | Human Anatomy Department of Basic Sciences Aracatuba School of Dentistry Sao Paulo State University (UNESP) | - |
Descrição: dc.description | Oral and Maxillofacial Surgery Diagnostic and Surgery Aracatuba School of Dentistry Sao Paulo State University (UNESP) | - |
Descrição: dc.description | Human Anatomy Department of Basic Sciences Aracatuba School of Dentistry Sao Paulo State University (UNESP) | - |
Idioma: dc.language | en | - |
Relação: dc.relation | International Journal of Biomaterials | - |
???dc.source???: dc.source | Scopus | - |
Título: dc.title | Comparative Evaluation of Bone Repair with Four Different Bone Substitutes in Critical Size Defects | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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