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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Ghent University | - |
Autor(es): dc.contributor | VIB Center for Plant Systems Biology | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Institut Agro | - |
Autor(es): dc.contributor | VIB Metabolomics Core | - |
Autor(es): dc.creator | Ribeiro, Bianca | - |
Autor(es): dc.creator | Lacchini, Elia | - |
Autor(es): dc.creator | Bicalho, Keylla U. [UNESP] | - |
Autor(es): dc.creator | Mertens, Jan | - |
Autor(es): dc.creator | Arendt, Philipp | - |
Autor(es): dc.creator | Bossche, Robin Vanden | - |
Autor(es): dc.creator | Calegario, Gabriela | - |
Autor(es): dc.creator | Gryffroy, Lore | - |
Autor(es): dc.creator | Ceulemans, Evi | - |
Autor(es): dc.creator | Buitink, Julia | - |
Autor(es): dc.creator | Goossens, Alain | - |
Autor(es): dc.creator | Pollier, Jacob | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:31:03Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:31:03Z | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-06-01 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1105/tpc.19.00609 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/200554 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/200554 | - |
Descrição: dc.description | Plants produce a vast array of defense compounds to protect themselves from pathogen attack or herbivore predation. Saponins are a specific class of defense compounds comprising bioactive glycosides with a steroidal or triterpenoid aglycone backbone. The model legume Medicago truncatula synthesizes two types of saponins, hemolytic saponins and nonhemolytic soyasaponins, which accumulate as specific blends in different plant organs. Here, we report the identification of the seed-specific transcription factor TRITERPENE SAPONIN ACTIVATION REGULATOR3 (TSAR3), which controls hemolytic saponin biosynthesis in developing M. truncatula seeds. Analysis of genes that are coexpressed with TSAR3 in transcriptome data sets from developing M. truncatula seeds led to the identification of CYP88A13, a cytochrome P450 that catalyzes the C-16a hydroxylation of medicagenic acid toward zanhic acid, the final oxidation step of the hemolytic saponin biosynthesis branch in M. truncatula. In addition, two uridine diphosphate glycosyltransferases, UGT73F18 and UGT73F19, which glucosylate hemolytic sapogenins at the C-3 position, were identified. The genes encoding the identified biosynthetic enzymes are present in clusters of duplicated genes in the M. truncatula genome. This appears to be a common theme among saponin biosynthesis genes, especially glycosyltransferases, and may be the driving force of the metabolic evolution of saponins. | - |
Descrição: dc.description | Ghent University Department of Plant Biotechnology and Bioinformatics | - |
Descrição: dc.description | VIB Center for Plant Systems Biology | - |
Descrição: dc.description | Department of Organic Chemistry Institute of Chemistry São Paulo State University (UNESP) | - |
Descrição: dc.description | Institut de Recherche en Horticulture et Semences-Unités Mixtes de Recherche Université d’Angers INRAE Institut Agro, SFR 4207 QuaSaV | - |
Descrição: dc.description | VIB Metabolomics Core | - |
Descrição: dc.description | Department of Organic Chemistry Institute of Chemistry São Paulo State University (UNESP) | - |
Formato: dc.format | 2020-2042 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Plant Cell | - |
???dc.source???: dc.source | Scopus | - |
Título: dc.title | A seed-specific regulator of triterpene saponin biosynthesis in medicago truncatula | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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