Incidence and risk factors for hyperglycemia in pregnancy among nulliparous women: A Brazilian multicenter cohort study

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorFederal University of Ceará-
Autor(es): dc.contributorUniversidade Federal de Pernambuco (UFPE)-
Autor(es): dc.contributorFederal University of RS-
Autor(es): dc.contributorJundiaí-
Autor(es): dc.contributorUniversity of Leicester-
Autor(es): dc.contributorUniversity of Liverpool-
Autor(es): dc.creatorNicolosi, Bianca F. [UNESP]-
Autor(es): dc.creatorSouza, Renato T.-
Autor(es): dc.creatorMayrink, Jussara-
Autor(es): dc.creatorFeitosa, Francisco E.-
Autor(es): dc.creatorRocha Filho, Edilberto A.-
Autor(es): dc.creatorLeite, Débora F.-
Autor(es): dc.creatorVettorazzi, Janete-
Autor(es): dc.creatorSousa, Maria H.-
Autor(es): dc.creatorCosta, Maria L.-
Autor(es): dc.creatorBaker, Philip N.-
Autor(es): dc.creatorKenny, Louise C.-
Autor(es): dc.creatorCecatti, Jose G.-
Autor(es): dc.creatorCalderon, Iracema M. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:30:30Z-
Data de disponibilização: dc.date.available2022-02-22T00:30:30Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-05-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1371/journal.pone.0232664-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200402-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200402-
Descrição: dc.descriptionObjective To assess the incidence and risk factors for hyperglycemia in pregnancy in a cohort of Brazilian nulliparous pregnant women. Materials and methods This is a secondary analysis of a multicenter cohort study that enrolled 1,008 nulliparous pregnant women at 19–21 weeks. Exclusion criteria included chronic exposure to corticosteroids and previous diabetes. Bivariate and multivariate analyses by Poisson regression were used to identify associated factors. Results The incidence of hyperglycemia in pregnancy was 14.9% (150/1,008), and 94.7% of these cases were gestational diabetes mellitus (142/150). Significant associated factors included a family history of diabetes mellitus, maternal overweight or obesity at enrollment, and previous maternal conditions (polycystic ovarian syndrome, thyroid dysfunctions and hypertensive disorders). A BMI ≥ 26.3Kg/m2 (RRadj 1.87 [1.66–2.10]) and a family history of diabetes mellitus (RRadj 1.71 [1.37–2.15]) at enrollment were independent risk factors for HIP. Conclusions A family history of diabetes mellitus and overweight or obesity (until 19–21 weeks of gestation) may be used as selective markers for HIP in Brazilian nulliparous women. Given the scarcity of results in nulliparous women, our findings may contribute to determine the optimal diagnostic approach in populations of similar socioeconomic characteristics.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionBill and Melinda Gates Foundation-
Descrição: dc.descriptionDepartment of Obstetrics and Gynecology Botucatu Medical School Unesp-
Descrição: dc.descriptionDepartment of Obstetrics and Gynecology University of Campinas (UNICAMP) School of Medical Sciences-
Descrição: dc.descriptionMEAC–Maternity School of the Federal University of Ceará-
Descrição: dc.descriptionDepartment of Maternal and Child Health Maternity of Clinic Hospital Federal University of Pernambuco-
Descrição: dc.descriptionDepartment of Obstetrics and Gynecology Maternity of the Clinic Hospital Federal University of RS-
Descrição: dc.descriptionStatistics Unit Jundiai School of Medicine Jundiaí-
Descrição: dc.descriptionCollege of Life Sciences University of Leicester-
Descrição: dc.descriptionFaculty of Health and Life Sciences Department of Women’s and Children’s Health Institute of Translational Medicine University of Liverpool-
Descrição: dc.descriptionDepartment of Obstetrics and Gynecology Botucatu Medical School Unesp-
Descrição: dc.descriptionCNPq: 401636/2013-5-
Descrição: dc.descriptionBill and Melinda Gates Foundation: OPP1107597-
Idioma: dc.languageen-
Relação: dc.relationPLoS ONE-
???dc.source???: dc.sourceScopus-
Título: dc.titleIncidence and risk factors for hyperglycemia in pregnancy among nulliparous women: A Brazilian multicenter cohort study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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