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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual de Maringá (UEM) | - |
Autor(es): dc.contributor | UNIRP - University Center of Rio Preto | - |
Autor(es): dc.contributor | FACERES Medical School | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Universidade Federal do Paraná (UFPR) | - |
Autor(es): dc.contributor | Fundação Universidade Regional de Blumenau | - |
Autor(es): dc.creator | Freitas, Juliane Silberschmidt | - |
Autor(es): dc.creator | Pereira, Thiago Scremin Boscolo | - |
Autor(es): dc.creator | Boscolo, Camila Nomura Pereira | - |
Autor(es): dc.creator | Garcia, Mariana Navarro [UNESP] | - |
Autor(es): dc.creator | de Oliveira Ribeiro, Ciro Alberto | - |
Autor(es): dc.creator | de Almeida, Eduardo Alves | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:30:23Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:30:23Z | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-08-01 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1016/j.cbpc.2020.108770 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/200369 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/200369 | - |
Descrição: dc.description | Lubricant oils are among oil-based products that are not fully consumed during its use, thereby producing non-biodegradable residues which can cause contamination of natural systems. This study evaluated the toxicity of new and used lubricating oil (0.01 and 0.1 mL L−1) in adult Nile tilapia (Oreochromis niloticus), by assessing the effects on oxidative stress, biotransformation enzymes (liver and gills), and histopathological alterations on hepatic and pancreatic tissues after 3 and 7 days of exposure. Results showed that 3-days exposure to 0.1 mL L−1 of used and new lubricating oil increased the activity of superoxide dismutase (SOD) and malondialdehyde (MDA) levels in liver of O. niloticus, respectively. In gills, catalase (CAT) was decreased in fish exposed to 0.1 mL L−1 of non-used oil after 3 days, but pronounced increases in CAT was detected after 7 days-exposure to both new and used oil. Shorter exposure to both concentrations of new and used oil also raised glutathione-S-transferase activity (GST) in gills. Ethoxyresorufin-O-deethylase (EROD) was induced in liver of fish exposed to 0.1 mL L−1of used oil after 3 and 7 days, however a reduced response of this enzyme was detected in gills of animals from both oil treatments. In vitro analysis showed that hepatic EROD was inhibited by lubricating oil exposures, with more pronounced responses in treatments containing used oil. Hepatic lesions, such as cytoplasmic vacuolization, nuclei abnormally, changes in hepatocytes shape, steatosis, cholestasis, eosinophilic inclusions and necrosis were mainly increased by 7 days exposure to used lubricating oil at higher concentration. | - |
Descrição: dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
Descrição: dc.description | Department of Biology Minas Gerais State University (UEMG), R. Ver. Geraldo Moisés da Silva, s/n - Universitário | - |
Descrição: dc.description | UNIRP - University Center of Rio Preto | - |
Descrição: dc.description | FACERES - Morfofunctional Laboratory FACERES Medical School | - |
Descrição: dc.description | Department of Chemistry and Environmental Science Universidade Estadual Paulista (IBILCE/UNESP), R. Critóvão Colombo, 2265 | - |
Descrição: dc.description | Department of Cell Biology Universidade Federal do Paraná, Centro Politécnico, 19031 | - |
Descrição: dc.description | Department of Natural Sciences Fundação Universidade Regional de Blumenau, Av. Antonio da Veiga 140, Itoupava Seca | - |
Descrição: dc.description | Department of Chemistry and Environmental Science Universidade Estadual Paulista (IBILCE/UNESP), R. Critóvão Colombo, 2265 | - |
Descrição: dc.description | FAPESP: 2006/03873-1 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Antioxidant enzymes | - |
Palavras-chave: dc.subject | Biotransformation | - |
Palavras-chave: dc.subject | Fish | - |
Palavras-chave: dc.subject | Histopathology | - |
Palavras-chave: dc.subject | Lubricating oil | - |
Título: dc.title | Oxidative stress, biotransformation enzymes and histopathological alterations in Nile tilapia (Oreochromis niloticus) exposed to new and used automotive lubricant oil | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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