Mesenchymal stem cell (MSc) secretome: A possible therapeutic strategy for intensive-care COVID-19 patients

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorDeffune, Elenice [UNESP]-
Autor(es): dc.creatorPrudenciatti, Aruã [UNESP]-
Autor(es): dc.creatorMoroz, Andrei [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:30:21Z-
Data de disponibilização: dc.date.available2022-02-22T00:30:21Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-09-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.mehy.2020.109769-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200357-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200357-
Descrição: dc.descriptionAs an emerging global health challenge, COVID-19 requires international knowledge to reach novel possible therapeutic strategies, especially for intensive-care patients. During the early stages of infection, pneumocytes II are the primary infected cells, harming the respiratory system. We have previous evidence in murine models that MSc's secretome can be used to treat pulmonary injuries induced with bleomycin, due to its content: growth factors, extracellular vesicles, and exosomes. We hypothesize and strongly recommend MSc secretome testing and production, in xenofree conditions, to be used as an alternative approach in SARS-Cov-2 patients in critical conditions.-
Descrição: dc.descriptionSão Paulo State Univ UNESP Botucatu Medical School Blood Transfusion Center Cell Engineering Lab-
Descrição: dc.descriptionSão Paulo State Univ UNESP Araraquara School of Pharmaceutical Sciences Department of Clinical Analysis Laboratory of Monoclonal Antibodies-
Descrição: dc.descriptionSão Paulo State Univ UNESP Botucatu Medical School Blood Transfusion Center Cell Engineering Lab-
Descrição: dc.descriptionSão Paulo State Univ UNESP Araraquara School of Pharmaceutical Sciences Department of Clinical Analysis Laboratory of Monoclonal Antibodies-
Idioma: dc.languageen-
Relação: dc.relationMedical Hypotheses-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjectMSc secretome-
Palavras-chave: dc.subjectNovel strategy-
Título: dc.titleMesenchymal stem cell (MSc) secretome: A possible therapeutic strategy for intensive-care COVID-19 patients-
Aparece nas coleções:Repositório Institucional - Unesp

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