Candida Biofilms: An Update on Developmental Mechanisms and Therapeutic Challenges

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorde Barros, Patrícia Pimentel [UNESP]-
Autor(es): dc.creatorRossoni, Rodnei Dennis [UNESP]-
Autor(es): dc.creatorde Souza, Cheyenne Marçal [UNESP]-
Autor(es): dc.creatorScorzoni, Liliana [UNESP]-
Autor(es): dc.creatorFenley, Juliana De Camargo [UNESP]-
Autor(es): dc.creatorJunqueira, Juliana Campos [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:30:00Z-
Data de disponibilização: dc.date.available2022-02-22T00:30:00Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s11046-020-00445-w-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200267-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200267-
Descrição: dc.descriptionFungi of the genus Candida are important etiological agents of superficial and life-threatening infections in individuals with a compromised immune system. One of the main characteristics of Candida is its ability to form highly drug tolerance biofilms in the human host. Biofilms are a dynamic community of multiple cell types whose formation over time is orchestrated by a network of transcription regulators. In this brief review, we provide an update of the processes involved in biofilm formation by Candida spp. (formation, treatment, and control), as well as the transcriptional circuitry that regulates its development and interactions with other microorganisms. Candida albicans is known to build mixed species biofilms with other Candida species and with various other bacterial species in different host niches. Taken together, these properties play a key role in Candida pathogenesis. In addition, this review gathers recent studies with new insights and perspectives for the treatment and control of Candida biofilms.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionDepartment of Biosciences and Oral Diagnosis São Paulo State University (Unesp) Institute of Science and Technology São José dos Campos, Avenida Engenheiro Francisco José Longo 777, São Dimas-
Descrição: dc.descriptionDepartment of Biosciences and Oral Diagnosis São Paulo State University (Unesp) Institute of Science and Technology São José dos Campos, Avenida Engenheiro Francisco José Longo 777, São Dimas-
Descrição: dc.descriptionFAPESP: 2017/02652-6-
Descrição: dc.descriptionFAPESP: 2017/19219-3-
Descrição: dc.descriptionFAPESP: 2019/05664-0-
Descrição: dc.descriptionCNPq: 306330/2018-0-
Formato: dc.format415-424-
Idioma: dc.languageen-
Relação: dc.relationMycopathologia-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAlternative treatment-
Palavras-chave: dc.subjectBiofilms-
Palavras-chave: dc.subjectCandida spp-
Palavras-chave: dc.subjectPolymicrobial biofilms-
Palavras-chave: dc.subjectTranscriptional circuitry-
Título: dc.titleCandida Biofilms: An Update on Developmental Mechanisms and Therapeutic Challenges-
Aparece nas coleções:Repositório Institucional - Unesp

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