Can photobiomodulation therapy (PBMT) control blood glucose levels and alter muscle glycogen synthesis?

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Autor(es): dc.contributorUniversidade Brasil-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorBauru-
Autor(es): dc.creatorCastro, Kenia Mendes Rodrigues-
Autor(es): dc.creatorde Paiva Carvalho, Rodrigo Leal [UNESP]-
Autor(es): dc.creatorJunior, Geraldo Marco Rosa-
Autor(es): dc.creatorTavares, Beatriz Antoniassi-
Autor(es): dc.creatorSimionato, Luis Henrique-
Autor(es): dc.creatorBortoluci, Carlos Henrique Fachin-
Autor(es): dc.creatorSoto, Claudio Alberto Tellez-
Autor(es): dc.creatorFerraresi, Cleber-
Data de aceite: dc.date.accessioned2022-02-22T00:29:59Z-
Data de disponibilização: dc.date.available2022-02-22T00:29:59Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jphotobiol.2020.111877-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200261-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200261-
Descrição: dc.descriptionPhotobiomodulation therapy (PBMT) has many effects on the energy metabolism of musculoskeletal tissue, such as increased glycogen and adenosine triphosphate synthesis. In addition, these effects may be due to a systemic blood glucose control. Twenty-four Wistar rats were randomly and equally allocated into four groups: sham, PBMT 10 J/cm2, PBMT 30 J/cm2 and PBMT 60 J/cm2. The animals were fasting for 6 h for blood glucose evaluations during pre-irradiation period, 1 h, 3 h and 6 h after PBMT. Muscle glycogen synthesis was measured 24 h after PBMT. This PBMT used a cluster of 69 LEDs (light-emitting diodes) with 35 red (630 ± 10 nm) and 34 infrared (850 ± 20 nm); 114 mW/cm2 for 90s (10 J/cm2), 270 s (30 J/cm2), 540 s (60 J/cm2) applied on large muscle areas (back and hind legs) of the animals. The 10 J/cm2 group showed lower blood glucose levels and glucose variability over 6 h (5.92 mg/dL) compared to the sham (13.03 mg/dL), 30 J/cm2 (7.77 mg/dL) and 60 J/cm2 (9.07 mg/dL) groups. The PBMT groups had the greatest increase in muscle glycogen (10 J/cm2 > 60 J/cm2 > 30 J/cm2 > sham), characterizing a triphasic dose-response of PBMT. There was a strong negative correlation between blood glucose variability over 6 h and muscle glycogen concentration for 10 J/cm2 group (r = −0.94; p < .001) followed by 30 J/cm2 group (r = −0.84; p < .001) and 60 J/cm2 group(r = −0.73; p < .006). These results suggest that PBMT can play a very important role in the control of blood glucose levels, and its possible mechanism of action is the induction of greater muscle glycogen synthesis independently of physical exercise.-
Descrição: dc.descriptionPost-Graduation Program in Biomedical Engineering Universidade Brasil-
Descrição: dc.descriptionLaboratory of Physiology and Human Performance São Paulo State University – UNESP, Bauru-
Descrição: dc.descriptionUniversidade do Sagrado Coração (USC) Bauru-
Descrição: dc.descriptionLaboratory of Physiology and Human Performance São Paulo State University – UNESP, Bauru-
Idioma: dc.languageen-
Relação: dc.relationJournal of Photochemistry and Photobiology B: Biology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBlood glucose-
Palavras-chave: dc.subjectDiabetes mellitus-
Palavras-chave: dc.subjectGlycogen-
Palavras-chave: dc.subjectLED therapy-
Palavras-chave: dc.subjectLow-level laser therapy-
Título: dc.titleCan photobiomodulation therapy (PBMT) control blood glucose levels and alter muscle glycogen synthesis?-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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