Phytochemical analysis of the methanolic leaves extract of Niedenzuella multiglandulosa (Malpighiaceae), a plant species toxic to cattle in Brazil

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversity of Lausanne-
Autor(es): dc.contributorUniversidade Federal de Minas Gerais (UFMG)-
Autor(es): dc.contributorUniversidade Federal de Mato Grosso do Sul (UFMS)-
Autor(es): dc.creatorMannochio Russo, Helena [UNESP]-
Autor(es): dc.creatorFerreira Queiroz, Emerson-
Autor(es): dc.creatorMarcourt, Laurence-
Autor(es): dc.creatorRutz, Adriano-
Autor(es): dc.creatorAllard, Pierre-Marie-
Autor(es): dc.creatorde Almeida, Rafael Felipe-
Autor(es): dc.creatorMarques Carvalho, Nilton-
Autor(es): dc.creatorWolfender, Jean-Luc-
Autor(es): dc.creatorda Silva Bolzani, Vanderlan [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:29:41Z-
Data de disponibilização: dc.date.available2022-02-22T00:29:41Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.phytol.2020.02.005-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200179-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200179-
Descrição: dc.descriptionNiedenzuella multiglandulosa (Malpighiaceae) is a neotropical liana responsible for cattle intoxication outbreaks in Brazil that may lead to abortion and even death of the animals, causing substantial losses in Brazilian trade balance. A phytochemical study of N. multiglandulosa leaves was performed in order to obtain chemical information about secondary metabolites of this poorly studied species. The methanolic extract was purified by medium pressure liquid chromatography (MPLC) combined with semi preparative HPLC-PDA leading to the isolation of 16 compounds, including a new steroid named 5-hydroxypodecdysone B (13). The structure of the isolated compounds was determined by classical spectroscopic methods such as NMR and HRMS. Complementary 19F NMR and UPLC-HRMS analysis did not detect the presence of monofluoracetate (MFA), a toxic compound previously described from this species.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung-
Descrição: dc.descriptionNucleus of Bioassays Biosynthesis and Ecophysiology of Natural Products (NuBBE) Department of Organic Chemistry Institute of Chemistry São Paulo State University (UNESP)-
Descrição: dc.descriptionSchool of Pharmaceutical Sciences University of Geneva University of Lausanne, 1, Rue Michel-Servet-
Descrição: dc.descriptionDepartament of Botany Institute of Biological Sciences Federal University of Minas Gerais (UFMG), Belo Horizonte-
Descrição: dc.descriptionFaculty of Veterinary Medicine and Zootechnics (FAMEZ) Feredal University of Mato Grosso do Sul (UFMS), Campo Grande-
Descrição: dc.descriptionNucleus of Bioassays Biosynthesis and Ecophysiology of Natural Products (NuBBE) Department of Organic Chemistry Institute of Chemistry São Paulo State University (UNESP)-
Descrição: dc.descriptionSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung: 316030_164095-
Formato: dc.format10-16-
Idioma: dc.languageen-
Relação: dc.relationPhytochemistry Letters-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCattle intoxication-
Palavras-chave: dc.subjectIsolation steroids-
Palavras-chave: dc.subjectMetabolite profile-
Palavras-chave: dc.subjectMonofluoracetate (MFA)-
Palavras-chave: dc.subjectNiedenzuella multiglandulosa-
Palavras-chave: dc.subjectUHPLC-PDA-HRMS-
Título: dc.titlePhytochemical analysis of the methanolic leaves extract of Niedenzuella multiglandulosa (Malpighiaceae), a plant species toxic to cattle in Brazil-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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