Advances and challenges in nanocarriers and nanomedicines for veterinary application

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorLaboratory of Pharmaceutical Production-
Autor(es): dc.creatorCarvalho, Suzana Gonçalves [UNESP]-
Autor(es): dc.creatorAraujo, Victor Hugo Sousa [UNESP]-
Autor(es): dc.creatordos Santos, Aline Martins [UNESP]-
Autor(es): dc.creatorDuarte, Jonatas Lobato [UNESP]-
Autor(es): dc.creatorSilvestre, Amanda Letícia Polli [UNESP]-
Autor(es): dc.creatorFonseca-Santos, Bruno-
Autor(es): dc.creatorVillanova, Janaina Cecília Oliveira-
Autor(es): dc.creatorGremião, Maria Palmira Daflon [UNESP]-
Autor(es): dc.creatorChorilli, Marlus [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:29:39Z-
Data de disponibilização: dc.date.available2022-02-22T00:29:39Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-04-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.ijpharm.2020.119214-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200171-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200171-
Descrição: dc.descriptionTo ensure success in the development and manufacturing of nanomedicines requires forces of an interdisciplinary team that combines medicine, engineering, chemistry, biology, material and pharmaceutical areas. Numerous researches in nanotechnology applied to human health are available in the literature. Althought, the lack of nanotechnology-based pharmaceuticals products for use exclusively in veterinary pharmacotherapy creates a potential area for the development of innovative products, as these animal health studies are still scarce when compared to studies in human pharmacotherapy. Nano-dosage forms can ensure safer and more effective pharmacotherapy for animals and can more be safer for the consumers of livestock products, once they can offer higher selectivity and smaller toxicity associated with lower doses of the drugs. In addition, the development and production of nanomedicines may consolidate the presence of pharmaceutical laboratories in the global market and can generate greater profit in a competitive business environment. To contribute to this scenario, this article provides a review of the main nanocarriers used in nanomedicines for veterinary use, with emphasis on liposomes, nanoemulsions, micelles, lipid nanoparticles, polymeric nanoparticles, mesoporous silica nanoparticles, metallic nanoparticles and dendrimers, and the state of the art of application of these nanocarriers in drug delivery systems to animal use. Finnaly, the major challenges involved in research, scale-up studies, large-scale manufacture, analytical methods for quality assessment, and regulatory aspects of nanomedicines were discussed.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionUniversidade Estadual Paulista-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionDepartment of Drugs and Medicines School of Pharmaceutical Sciences – São Paulo State University (UNESP)-
Descrição: dc.descriptionFaculty of Pharmaceutical Sciences University of Campinas (UNICAMP)-
Descrição: dc.descriptionLaboratory of Pharmaceutical Production Departament of Pharmacy and Nutrition – Federal University of Espirito Santo (UFES)-
Descrição: dc.descriptionDepartment of Drugs and Medicines School of Pharmaceutical Sciences – São Paulo State University (UNESP)-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionCNPq: 142214/2019-1-
Idioma: dc.languageen-
Relação: dc.relationInternational Journal of Pharmaceutics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDrug delivery systems-
Palavras-chave: dc.subjectNanocarriers-
Palavras-chave: dc.subjectNanomedicines-
Palavras-chave: dc.subjectRegulatory aspects-
Palavras-chave: dc.subjectVeterinary pharmaceutical products-
Título: dc.titleAdvances and challenges in nanocarriers and nanomedicines for veterinary application-
Aparece nas coleções:Repositório Institucional - Unesp

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