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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade de São Paulo (USP) | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | University of Marilia (UNIMAR) | - |
Autor(es): dc.contributor | University Center of Adamantina (UniFAI) | - |
Autor(es): dc.contributor | University of the Sacred Heart (USC) | - |
Autor(es): dc.creator | de Oliveira Rosso, Marcelie Priscila | - |
Autor(es): dc.creator | Oyadomari, Aline Tiemi | - |
Autor(es): dc.creator | Pomini, Karina Torres | - |
Autor(es): dc.creator | Coletta, Bruna Botteon Della | - |
Autor(es): dc.creator | Shindo, João Vitor Tadashi Cosin | - |
Autor(es): dc.creator | Júnior, Rui Seabra Ferreira [UNESP] | - |
Autor(es): dc.creator | Barraviera, Benedito [UNESP] | - |
Autor(es): dc.creator | Cassaro, Claudia Vilalva [UNESP] | - |
Autor(es): dc.creator | Buchaim, Daniela Vieira | - |
Autor(es): dc.creator | Teixeira, Daniel de Bortoli | - |
Autor(es): dc.creator | Barbalho, Sandra Maria | - |
Autor(es): dc.creator | Alcalde, Murilo Priori | - |
Autor(es): dc.creator | Duarte, Marco Antonio Hungaro | - |
Autor(es): dc.creator | Andreo, Jesus Carlos | - |
Autor(es): dc.creator | Buchaim, Rogério Leone | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:29:28Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:29:28Z | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-03-01 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.3390/biom10030383 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/200123 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/200123 | - |
Descrição: dc.description | Bone defects cause aesthetic and functional changes that affect the social, economic and especially the emotional life of human beings. This complication stimulates the scientific community to investigate strategies aimed at improving bone reconstruction processes using complementary therapies. Photobiomodulation therapy (PBMT) and the use of new biomaterials, including heterologous fibrin biopolymer (HFB), are included in this challenge. The objective of the present study was to evaluate the influence of photobiomodulation therapy on bone tibial reconstruction of rats with biomaterial consisting of lyophilized bovine bone matrix (BM) associated or not with heterologous fibrin biopolymer. Thirty male rats were randomly separated into three groups of 10 animals. In all animals, after the anesthetic procedure, a noncritical tibial defect of 2 mm was performed. The groups received the following treatments: Group 1: BM + PBMT, Group 2: BM + HFB and Group 3: BM + HFB + PBMT. The animals from Groups 1 and 3 were submitted to PBMT in the immediate postoperative period and every 48 h until the day of euthanasia that occurred at 14 and 42 days. Analyses by computed microtomography (µCT) and histomorphometry showed statistical difference in the percentage of bone formation between Groups 3 (BM + HB + PBMT) and 2 (BM + HFB) (26.4% ± 1.03% and 20.0% ± 1.87%, respectively) at 14 days and at 42 days (38.2% ± 1.59% and 31.6% ± 1.33%, respectively), and at 42 days there was presence of bone with mature characteristics and organized connective tissue. The µCT demonstrated BM particles filling the defect and the deposition of new bone in the superficial region, especially in the ruptured cortical. It was concluded that the association of PBMT with HFB and BM has the potential to assist in the process of reconstructing bone defects in the tibia of rats. | - |
Descrição: dc.description | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | - |
Descrição: dc.description | Department of Biological Sciences (Anatomy) Bauru School of Dentistry University of São Paulo (USP), Alameda Dr. Octávio Pinheiro Brisolla, 9-75-Vila Universitaria | - |
Descrição: dc.description | Center for the Study of Venoms and Venomous Animals (CEVAP) São Paulo State University (Univ. Estadual Paulista UNESP), São Paulo | - |
Descrição: dc.description | University of Marilia (UNIMAR), Avenue Hygino Muzzy Filho, 1001 | - |
Descrição: dc.description | Medical School University Center of Adamantina (UniFAI), Nove de Julho Street, 730-Centro | - |
Descrição: dc.description | Department of Health Science University of the Sacred Heart (USC) | - |
Descrição: dc.description | Department of Dentistry Endodontics and Dental Materials Bauru School of Dentistry University of São Paulo (USP) | - |
Descrição: dc.description | Center for the Study of Venoms and Venomous Animals (CEVAP) São Paulo State University (Univ. Estadual Paulista UNESP), São Paulo | - |
Descrição: dc.description | CAPES: 001 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Biomolecules | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Biomaterials | - |
Palavras-chave: dc.subject | Bone regeneration | - |
Palavras-chave: dc.subject | Fibrin biopolymer | - |
Palavras-chave: dc.subject | Low-level laser therapy | - |
Palavras-chave: dc.subject | Photobiomodulation therapy | - |
Título: dc.title | Photobiomodulation therapy associated with heterologous fibrin biopolymer and bovine bone matrix helps to reconstruct long bones | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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