Modification of the head proteome of nurse honeybees (Apis mellifera) exposed to field-relevant doses of pesticides

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Federal de Mato Grosso do Sul (UFMS)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorZaluski, Rodrigo-
Autor(es): dc.creatorBittarello, Alis Correia [UNESP]-
Autor(es): dc.creatorVieira, José Cavalcante Souza [UNESP]-
Autor(es): dc.creatorBraga, Camila Pereira [UNESP]-
Autor(es): dc.creatorPadilha, Pedro de Magalhaes [UNESP]-
Autor(es): dc.creatorFernandes, Mileni da Silva-
Autor(es): dc.creatorBovi, Thaís de Souza [UNESP]-
Autor(es): dc.creatorOrsi, Ricardo de Oliveira [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:29:14Z-
Data de disponibilização: dc.date.available2022-02-22T00:29:14Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1038/s41598-020-59070-8-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200054-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200054-
Descrição: dc.descriptionUnderstanding the effect of pesticides on the survival of honeybee colonies is important because these pollinators are reportedly declining globally. In the present study, we examined the changes in the head proteome of nurse honeybees exposed to individual and combined pesticides (the fungicide pyraclostrobin and the insecticide fipronil) at field-relevant doses (850 and 2.5 ppb, respectively). The head proteomes of bees exposed to pesticides were compared with those of bees that were not exposed, and proteins with differences in expression were identified by mass spectrometry. The exposure of nurse bees to pesticides reduced the expression of four of the major royal jelly proteins (MRJP1, MRJP2, MRJP4, and MRJP5) and also several proteins associated with carbohydrate metabolism and energy synthesis, the antioxidant system, detoxification, biosynthesis, amino acid metabolism, transcription and translation, protein folding and binding, olfaction, and learning and memory. Overall, when pyraclostrobin and fipronil were combined, the changes in protein expression were exacerbated. Our results demonstrate that vital proteins and metabolic processes are impaired in nurse honeybees exposed to pesticides in doses close to those experienced by these insects in the field, increasing their susceptibility to stressors and affecting the nutrition and maintenance of both managed and natural colonies.-
Descrição: dc.descriptionGrupo de Estudos em Apicultura e Meliponicultura Sustentável de Mato Grosso do Sul - GEAMS Federal University of Mato Grosso do Sul (UFMS) Faculty of Veterinary Medicine and Animal Science (FAMEZ)-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Biosciences Department of Chemistry and Biochemistry-
Descrição: dc.descriptionFederal University of Mato Grosso do Sul (UFMS) Institute of Chemistry (INQUI)-
Descrição: dc.descriptionUniversity of São Paulo (USP) Bauru Dental School-
Descrição: dc.descriptionNúcleo de Ensino Ciência e Tecnologia em Apicultura Racional (NECTAR) São Paulo State University (UNESP) School of Veterinary Medicine and Animal Science Department of Animal Production-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Biosciences Department of Chemistry and Biochemistry-
Descrição: dc.descriptionNúcleo de Ensino Ciência e Tecnologia em Apicultura Racional (NECTAR) São Paulo State University (UNESP) School of Veterinary Medicine and Animal Science Department of Animal Production-
Idioma: dc.languageen-
Relação: dc.relationScientific Reports-
???dc.source???: dc.sourceScopus-
Título: dc.titleModification of the head proteome of nurse honeybees (Apis mellifera) exposed to field-relevant doses of pesticides-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.