Oral granular cell tumour: A multicentric study of 56 cases and a systematic review

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Autor(es): dc.contributorUniversity of the Basque Country-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorMogi das Cruzes University-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorInstituto de Investigación Sanitaria de Santiago (IDIS)-
Autor(es): dc.creatorLafuente Ibáñez de Mendoza, Irene-
Autor(es): dc.creatorLópez Ortega, Karem-
Autor(es): dc.creatorTrierveiler, Marília-
Autor(es): dc.creatorOliveira Alves, Monica Ghislaine-
Autor(es): dc.creatorDias Almeida, Janete [UNESP]-
Autor(es): dc.creatorGándara Vila, Pilar-
Autor(es): dc.creatorAguirre Urízar, José Manuel-
Autor(es): dc.creatorPérez Sayans, Mario-
Data de aceite: dc.date.accessioned2022-02-22T00:29:07Z-
Data de disponibilização: dc.date.available2022-02-22T00:29:07Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-04-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1111/odi.13273-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/200020-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/200020-
Descrição: dc.descriptionObjective: Granular cell tumour (GCT) is a benign neoplasm that originates from Schwann cells. Within the oral cavity, it usually appears as a lingual nodule and especially amongst female adults. Histologically, GCT shows a proliferation of polygonal cells with eosinophilic granular cytoplasm, which can be associated with a pseudoepitheliomatous hyperplasia (PEH). In this study, we analyse the main clinicopathological data of intraoral GCT and we compare our results with previous studies. Material and Methods: We have studied a series of 56 cases of oral GCT in Spain and Brazil, and we have conducted a systematic review in PubMed, Web of Knowledge and Scopus databases, using the keywords: “granular cell tumour” and oral. Results: In our series, GCT appeared as an asymptomatic benign tumour that is more frequent in women and in the tongue. PEH was observed in 32% of the lesions. In the review, we collected 282 cases of oral GCT with a similar clinical profile; seven patients had multiple lesions, and 33% of the cases presented PEH. No cases of malignant oral GCT have been described to date. GCT is an uncommon oral benign neoplasm, mainly unique and asymptomatic, derived from Schwann cells. Conclusions: Although the etiopathogenesis of this oral tumour is unknown, its characteristics suggest that it could have a reactive nature. Conducting a complete clinicopathological study in all intraoral GCT is fundamental in order to dismiss other entities, including oral carcinoma.-
Descrição: dc.descriptionOral and Maxillofacial Pathology and Oral Medicine Unit Department of Stomatology II University of the Basque Country-
Descrição: dc.descriptionSpecial Care Dentistry Centre (CAPE) and Oral Pathology Department of Stomatology University of São Paulo School of Dentistry (USP)-
Descrição: dc.descriptionMogi das Cruzes University-
Descrição: dc.descriptionDepartment of Bioscience and Oral Diagnosis Institute of Science and Technology of São José dos Campos São Paulo State University (Unesp)-
Descrição: dc.descriptionOral Medicine Oral Surgery and Implantology Unit MedOralRes Group Universidade de Santiago de Compostela Instituto de Investigación Sanitaria de Santiago (IDIS)-
Descrição: dc.descriptionDepartment of Bioscience and Oral Diagnosis Institute of Science and Technology of São José dos Campos São Paulo State University (Unesp)-
Formato: dc.format573-589-
Idioma: dc.languageen-
Relação: dc.relationOral Diseases-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectetiopathogenesis-
Palavras-chave: dc.subjectgranular cell tumour-
Palavras-chave: dc.subjectmulticentric study-
Palavras-chave: dc.subjectsystematic review-
Título: dc.titleOral granular cell tumour: A multicentric study of 56 cases and a systematic review-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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