Influence of anti-allergic drugs used systemically on the process of root resorption during delayed tooth replantation: A study in rats

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversity of Western São Paulo-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorMachado, Nathália Evelyn da Silva [UNESP]-
Autor(es): dc.creatorBanci, Henrique Augusto [UNESP]-
Autor(es): dc.creatorda Silva, Lucas Deszo-
Autor(es): dc.creatorSantinoni, Carolina dos Santos-
Autor(es): dc.creatorde Oliveira, Danilo Louzada-
Autor(es): dc.creatorErvolino, Edilson [UNESP]-
Autor(es): dc.creatorPrado, Rosana Leal do-
Autor(es): dc.creatorMori, Graziela Garrido-
Data de aceite: dc.date.accessioned2022-02-22T00:28:54Z-
Data de disponibilização: dc.date.available2022-02-22T00:28:54Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1111/edt.12535-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/199954-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/199954-
Descrição: dc.descriptionBackground/Aim: Anti-allergic drugs can inhibit the hard tissue resorption process, and due to similarities between root resorption and bone mechanisms, it can be inferred that these drugs may also control root resorption. The aim of this study was to analyze the effects of anti-allergic drugs used systemically on the process of root resorption following delayed tooth replantation. Materials and Methods: Thirty-two maxillary right incisors of rats were extracted and subsequently replanted. Rats were divided into four groups according to the anti-allergic drug administered: the rats in groups DEX, Q, and MO were treated systemically with dexamethasone phosphate, quercetin, and montelukast, respectively, and no systemic medication was administered to rats in group C. After 60 days, the animals were euthanized, and the specimens were processed for histomorphometric and immunohistochemical analyses. Statistical significance was set at P <.05. Results: There were no significant differences between the groups in terms of inflammatory resorption, replacement resorption, or presence of tartrate-resistant acid phosphatase. In terms of events occurring in the periodontal ligament space, there was a difference between groups Q and MO due to the presence of dental ankylosis and inflammatory connective tissue (P <.05). A difference in inflammatory cells was also observed through CD45 immunolabeling between the DEX and Q groups when compared to the C group (P <.05). Conclusion: The systemic administration of anti-allergic drugs did not have an effect on the process of root resorption following delayed tooth replantation.-
Descrição: dc.descriptionGraduate Program in Dentistry University of Western São Paulo-
Descrição: dc.descriptionDepartment of Endodontics Araçatuba Dental School UNESP – University Estadual Paulista-
Descrição: dc.descriptionDental School of Presidente Prudente University of Western São Paulo-
Descrição: dc.descriptionDepartment of Basic Science Araçatuba Dental School UNESP – University Estadual Paulista-
Descrição: dc.descriptionDepartment of Endodontics Araçatuba Dental School UNESP – University Estadual Paulista-
Descrição: dc.descriptionDepartment of Basic Science Araçatuba Dental School UNESP – University Estadual Paulista-
Formato: dc.format264-271-
Idioma: dc.languageen-
Relação: dc.relationDental Traumatology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectanti-allergic agents-
Palavras-chave: dc.subjectroot resorption-
Palavras-chave: dc.subjecttooth replantation-
Título: dc.titleInfluence of anti-allergic drugs used systemically on the process of root resorption during delayed tooth replantation: A study in rats-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.