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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | University of Birmingham | - |
Autor(es): dc.contributor | UPS | - |
Autor(es): dc.contributor | University of Nottingham | - |
Autor(es): dc.contributor | South Kensington Campus | - |
Autor(es): dc.creator | Decio, Pâmela [UNESP] | - |
Autor(es): dc.creator | Ustaoglu, Pinar | - |
Autor(es): dc.creator | Roat, Thaisa C. [UNESP] | - |
Autor(es): dc.creator | Malaspina, Osmar [UNESP] | - |
Autor(es): dc.creator | Devaud, Jean-Marc | - |
Autor(es): dc.creator | Stöger, Reinhard | - |
Autor(es): dc.creator | Soller, Matthias | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:28:25Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:28:25Z | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2019-11-30 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1038/s41598-019-55534-8 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/199822 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/199822 | - |
Descrição: dc.description | Securing food supply for a growing population is a major challenge and heavily relies on the use of agrochemicals to maximize crop yield. It is increasingly recognized, that some neonicotinoid insecticides have a negative impact on non-target organisms, including important pollinators such as the European honeybee Apis mellifera. Toxicity of neonicotinoids may be enhanced through simultaneous exposure with additional pesticides, which could help explain, in part, the global decline of honeybee colonies. Here we examined whether exposure effects of the neonicotinoid thiamethoxam on bee viability are enhanced by the commonly used fungicide carbendazim and the herbicide glyphosate. We also analysed alternative splicing changes upon pesticide exposure in the honeybee. In particular, we examined transcripts of three genes: (i) the stress sensor gene X box binding protein-1 (Xbp1), (ii) the Down Syndrome Cell Adhesion Molecule (Dscam) gene and iii) the embryonic lethal/abnormal visual system (elav) gene, which are important for neuronal function. Our results showed that acute thiamethoxam exposure is not enhanced by carbendazim, nor glyphosate. Toxicity of the compounds did not trigger stress-induced, alternative splicing in the analysed mRNAs, thereby leaving dormant a cellular response pathway to these man-made environmental perturbations. | - |
Descrição: dc.description | Biotechnology and Biological Sciences Research Council | - |
Descrição: dc.description | Universidade Estadual Paulista (UNESP) Instituto de Biociências Centro de Estudos de Insetos Sociais | - |
Descrição: dc.description | School of Biosciences College of Life and Environmental Sciences University of Birmingham | - |
Descrição: dc.description | Research Center on Animal Cognition Center for Integrative Biology Toulouse University CNRS UPS | - |
Descrição: dc.description | School of Biosciences University of Nottingham | - |
Descrição: dc.description | MRC Centre for Molecular Bacteriology and Infection and Department of Life Sciences Imperial College London Ground Floor Flowers Building South Kensington Campus | - |
Descrição: dc.description | Universidade Estadual Paulista (UNESP) Instituto de Biociências Centro de Estudos de Insetos Sociais | - |
Descrição: dc.description | Biotechnology and Biological Sciences Research Council: BB/K006827/1 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Scientific Reports | - |
???dc.source???: dc.source | Scopus | - |
Título: dc.title | Acute thiamethoxam toxicity in honeybees is not enhanced by common fungicide and herbicide and lacks stress-induced changes in mRNA splicing | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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