Genomic predictions for crossbred dairy cattle

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorAnimal Genomics and Improvement Laboratory-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorCouncil on Dairy Cattle Breeding-
Autor(es): dc.creatorVanRaden, P. M.-
Autor(es): dc.creatorTooker, M. E.-
Autor(es): dc.creatorChud, T. C.S. [UNESP]-
Autor(es): dc.creatorNorman, H. D.-
Autor(es): dc.creatorMegonigal, J. H.-
Autor(es): dc.creatorHaagen, I. W.-
Autor(es): dc.creatorWiggans, G. R.-
Data de aceite: dc.date.accessioned2022-02-22T00:28:23Z-
Data de disponibilização: dc.date.available2022-02-22T00:28:23Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3168/jds.2019-16634-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/199814-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/199814-
Descrição: dc.descriptionGenomic evaluations are useful for crossbred as well as purebred populations when selection is applied to commercial herds. Dairy farmers had already spent more than $1 million to genotype over 32,000 crossbred animals before US genomic evaluations became available for those animals. Thus, new tools were needed to provide accurate genomic predictions for crossbreds. Genotypes for crossbreds are imputed more accurately when the imputation reference population includes purebreds. Therefore, genotypes of 6,296 crossbred animals were imputed from lower-density chips by including either 3,119 ancestors or 834,367 genotyped animals in the reference population. Crossbreds in the imputation study included 733 Jersey × Holstein F1 animals, 55 Brown Swiss × Holstein F1 animals, 2,300 Holstein backcrosses, 2,026 Jersey backcrosses, 27 Brown Swiss backcrosses, and 502 other crossbreds of various breed combinations. Another 653 animals appeared to be purebreds that owners had miscoded as a different breed. Genomic breed composition was estimated from 60,671 markers using the known breed identities for purebred, progeny-tested Holstein, Jersey, Brown Swiss, Ayrshire, and Guernsey bulls as the 5 traits (breed fractions) to be predicted. Estimates of breed composition were adjusted so that no percentages were negative or exceeded 100%, and breed percentages summed to 100%. Another adjustment set percentages above 93.5% equal to 100%, and the resulting value was termed breed base representation (BBR). Larger percentages of missing alleles were imputed by using a crossbred reference population rather than only the closest purebred reference population. Crossbred predictions were averages of genomic predictions computed using marker effects for each pure breed, which were weighted by the animal's BBR. Marker and polygenic effects were estimated separately for each breed on the all-breed scale instead of within-breed scales. For crossbreds, genomic predictions weighted by BBR were more accurate than the average of parents' breeding values and slightly more accurate than predictions using only the predominant breed. For purebreds, single-trait predictions using only within-breed data were as accurate as multi-trait predictions with allele effects in different breeds treated as correlated effects. Crossbred genomic predicted transmitting abilities were implemented by the Council on Dairy Cattle Breeding in April 2019 and will aid producers in managing their breeding programs and selecting replacement heifers.-
Descrição: dc.descriptionUSDA Agricultural Research Service Animal Genomics and Improvement Laboratory-
Descrição: dc.descriptionDepartamento de Ciências Exatas Universidade Estadual Paulista (Unesp) Faculdade de Ciências Agrárias e Veterinárias, Jaboticabal-
Descrição: dc.descriptionCouncil on Dairy Cattle Breeding-
Descrição: dc.descriptionDepartamento de Ciências Exatas Universidade Estadual Paulista (Unesp) Faculdade de Ciências Agrárias e Veterinárias, Jaboticabal-
Formato: dc.format1620-1631-
Idioma: dc.languageen-
Relação: dc.relationJournal of Dairy Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectcrossbreeding-
Palavras-chave: dc.subjectgenomic evaluation-
Palavras-chave: dc.subjectimputation-
Palavras-chave: dc.subjectmultiple breed-
Título: dc.titleGenomic predictions for crossbred dairy cattle-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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