Mean arterial blood pressure: Potential predictive tool for preeclampsia in a cohort of healthy nulliparous pregnant women

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorFederal University of Ceará-
Autor(es): dc.contributorUniversidade Federal de Pernambuco (UFPE)-
Autor(es): dc.contributorFederal University of RS-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversity of Leicester-
Autor(es): dc.contributorUniversity of Liverpool-
Autor(es): dc.creatorMayrink, Jussara-
Autor(es): dc.creatorSouza, Renato T.-
Autor(es): dc.creatorFeitosa, Francisco E.-
Autor(es): dc.creatorRocha Filho, Edilberto A.-
Autor(es): dc.creatorLeite, Débora F.-
Autor(es): dc.creatorVettorazzi, Janete-
Autor(es): dc.creatorCalderon, Iracema M. [UNESP]-
Autor(es): dc.creatorCosta, Maria L.-
Autor(es): dc.creatorKenny, Louise-
Autor(es): dc.creatorBaker, Philip-
Autor(es): dc.creatorCecatti, Jose G.-
Autor(es): dc.creatorParpinelli, Mary A.-
Autor(es): dc.creatorFernandes, Karayna G.-
Autor(es): dc.creatorGuida, José P.-
Autor(es): dc.creatorSantana, Danielly-
Autor(es): dc.creatorGalvao, Rafael B. F.-
Autor(es): dc.creatorCassettari, Bianca F.-
Autor(es): dc.creatorPfitscher, Lucia-
Autor(es): dc.creatorDe Feitosa, Daisy Lucena-
Autor(es): dc.creatorDe Melo Ferreira Júnior, Elias-
Autor(es): dc.creatorAnacleto, Danilo-
Autor(es): dc.creatorZotareli, Vilma-
Autor(es): dc.creatorSilva, Marcia Alice-
Data de aceite: dc.date.accessioned2022-02-22T00:28:14Z-
Data de disponibilização: dc.date.available2022-02-22T00:28:14Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2019-12-02-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1186/s12884-019-2580-4-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/199750-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/199750-
Descrição: dc.descriptionBackground: Prediction of preeclampsia is a challenge to overcome. The vast majority of prospective studies in large general obstetric populations have failed in the purpose of obtain a useful and effective model of prediction, sometimes based on complex tools unavaible in areas where the incidence of preeclampsia is the highest. The goal of this study was to assess mean arterial blood pressure (MAP) levels at 19-21, 27-29 and 37-39 weeks of gestation and performance of screening by MAP for the prediction of preeclampsia in a Brazilian cohort of healthy nulliparous pregnant women. Methods: This was a cohort approach to a secondary analysis of the Preterm SAMBA study. Mean arterial blood pressure was evaluated at three different time periods during pregnancy. Groups with early-onset preeclampsia, late-onset preeclampsia and normotension were compared. Increments in mean arterial blood pressure between 20 and 27 weeks and 20 and 37 weeks of gestation were also calculated for the three groups studied. The accuracy of mean arterial blood pressure in the prediction of preeclampsia was determined by ROC curves. Results: Of the 1373 participants enrolled, complete data were available for 1165. The incidence of preeclampsia was 7.5%. Women with early-onset preeclampsia had higher mean arterial blood pressure levels at 20 weeks of gestation, compared to the normotensive group. Women with late-onset preeclampsia had higher mean arterial blood pressure levels at 37 weeks of gestation, than the normotensive groups and higher increases in this marker between 20 and 37 weeks of gestation. Based on ROC curves, the predictive performance of mean arterial blood pressure was higher at 37 weeks of gestation, with an area under the curve of 0.771. Conclusion: As an isolated marker for the prediction of preeclampsia, the performance of mean arterial blood pressure was low in a healthy nulliparous pregnant women group. Considering that early-onset preeclampsia cases had higher mean arterial blood pressure levels at 20 weeks of gestation, future studies with larger cohorts that combine multiple markers are needed for the development of a preeclampsia prediction model.-
Descrição: dc.descriptionDepartment of Obstetrics and Gynecology University of Campinas (UNICAMP) School of Medical Sciences, Rua Alexander Fleming, 101-
Descrição: dc.descriptionMEAC Maternity Hospital Federal University of Ceará-
Descrição: dc.descriptionDepartment of Maternal and Child Health Maternity Hospital Federal University of Pernambuco-
Descrição: dc.descriptionDepartment of Obstetrics and Gynecology Maternity Hospital Federal University of RS-
Descrição: dc.descriptionDepartment of Obstetrics and Gynecology Botucatu Medical School Unesp-
Descrição: dc.descriptionCollege of Life Sciences University of Leicester-
Descrição: dc.descriptionFaculty of Health and Life Sciences Department of Women's and Children's Health Institute of Translational Medicine University of Liverpool-
Descrição: dc.descriptionDepartment of Obstetrics and Gynecology Botucatu Medical School Unesp-
Idioma: dc.languageen-
Relação: dc.relationBMC Pregnancy and Childbirth-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBlood pressure-
Palavras-chave: dc.subjectHypertension-
Palavras-chave: dc.subjectPreeclampsia-
Palavras-chave: dc.subjectPrenatal screening-
Palavras-chave: dc.subjectSecond trimester-
Palavras-chave: dc.subjectThird trimester-
Título: dc.titleMean arterial blood pressure: Potential predictive tool for preeclampsia in a cohort of healthy nulliparous pregnant women-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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