Physicochemical characterization of bioactive compounds in nanocarriers

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual da Paraíba-
Autor(es): dc.contributorState University of Paraíba (UEPB)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidad de Castilla-La Mancha (UCLM)-
Autor(es): dc.creatorBarros, Rafaella Moreno-
Autor(es): dc.creatorde Oliveira, Maísa Soares-
Autor(es): dc.creatorCosta, Kammila Martins Nicolau-
Autor(es): dc.creatorSato, Mariana Rillo [UNESP]-
Autor(es): dc.creatorSantos, Karen Loraine Macena-
Autor(es): dc.creatorDamasceno, Bolívar Ponciano Goulart de Lima-
Autor(es): dc.creatorCuberes, Teresa-
Autor(es): dc.creatorOshiro-Junior, João Augusto-
Data de aceite: dc.date.accessioned2022-02-22T00:26:57Z-
Data de disponibilização: dc.date.available2022-02-22T00:26:57Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.2174/1381612826666200310144533-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/199279-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/199279-
Descrição: dc.descriptionThe encapsulation of bioactive compounds is an emerging technique for finding new medicines since it provides protection against ambient degradation factors before reaching the target site. Nanotechnology provides new methods for encapsulating bioactive compounds and for drug carrier development. Nanocarriers satisfactorily impact the absorption, distribution, metabolism, and excretion rate when compared to conventional carriers. The nanocarrier material needs to be compatible and bind to the drug and be bio-resorbable. In this context, the physicochemical characterization of encapsulated bioactive compounds is fundamental to guarantee the quality, reproducibility, and safety of the final pharmaceutical product. In this review, we present the physicochemical techniques most used today by researchers to characterize bioactive compounds in nanocarriers and the main information provided by each technique, such as morphology, size, degree of crystallinity, long-term stability, the efficacy of drug encapsulation, and the amount released as a function of time.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionUniversidade Estadual da Paraíba, Av. das Baraúnas, 351-
Descrição: dc.descriptionLaboratory of Development and Characterization of Pharmaceutical Products Department of Pharmacy Center for Biological and Health Sciences State University of Paraíba (UEPB)-
Descrição: dc.descriptionFaculdade de Ciências Farmacêuticas Universidade Estadual Paulista (UNESP), Araraquara-Jaú, Km 1-
Descrição: dc.descriptionLaboratorio de Nanotecnología Universidad de Castilla-La Mancha (UCLM), Plaza Manuel Meca 1-
Descrição: dc.descriptionFaculdade de Ciências Farmacêuticas Universidade Estadual Paulista (UNESP), Araraquara-Jaú, Km 1-
Formato: dc.format4163-4173-
Idioma: dc.languageen-
Relação: dc.relationCurrent Pharmaceutical Design-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiological activity-
Palavras-chave: dc.subjectIsolated compounds-
Palavras-chave: dc.subjectNanoparticles-
Palavras-chave: dc.subjectNanotechnology-
Título: dc.titlePhysicochemical characterization of bioactive compounds in nanocarriers-
Aparece nas coleções:Repositório Institucional - Unesp

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