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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | University Center of Maringa (UniCesumar) | - |
Autor(es): dc.contributor | Universidade de São Paulo (USP) | - |
Autor(es): dc.contributor | Federal University of Health Sciences of Porto Alegre (UFCSPA) | - |
Autor(es): dc.creator | Gerosa-Neto, José [UNESP] | - |
Autor(es): dc.creator | Monteiro, Paula Alves [UNESP] | - |
Autor(es): dc.creator | Inoue, Daniela Sayuri [UNESP] | - |
Autor(es): dc.creator | Antunes, Barbara Moura [UNESP] | - |
Autor(es): dc.creator | Batatinha, Helena | - |
Autor(es): dc.creator | Dorneles, Gilson Pires | - |
Autor(es): dc.creator | Peres, Alessandra | - |
Autor(es): dc.creator | Rosa-Neto, José Cesar | - |
Autor(es): dc.creator | Lira, Fabio Santos [UNESP] | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:26:54Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:26:54Z | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-11-30 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1016/j.cyto.2020.155249 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/199264 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/199264 | - |
Descrição: dc.description | The aim of this study was to evaluate the inflammatory (peripheral and lipopolysaccharide (LPS)-stimulated released from whole blood) and metabolic (glucose and insulin) profile of inactive obese men in response to two isoenergetic models of aerobic exercise training (~300 kcal each exercise session). Twenty-two participants (28.7 ± 1.6 years; BMI = 34.4 ± 0.1 kg/m2) were randomized into two groups: I) HIIT: high-intensity interval training (10× 1 bout: 1 min − 100% Maximal Aerobic Velocity) or II) MICT: moderate-intensity continuous training (65% Maximal Aerobic Velocity; kcal equal to HIIT). Both groups trained three times per week for 6-weeks. Fasting blood samples were collected before and 0, 30, and 60 min after exercise during the first and last training sessions for evaluation of: I) MIP-1ɑ, insulin, glucose, visceral and subcutaneous fat depots, oral glucose tolerance test, and homeostatic model assessment of insulin resistance (HOMA-IR) index; II) Peripheral (TNF-α, IL-6, and IL-10) and LPS-stimulated release of TNF-α and IL-10 were analyzed before, 0, and 60 min after sessions. IL-6 concentration remained elevated up to 60-min after the acute exercise session (p < 0.001), and IL-10 concentration was higher after 30 and 60-min (p = 0.001) compared to rest, independent of training period and protocol. AUC of IL-10 presented effect of type of training (p = 0.023) with MICT group showed significantly higher values than the HIIT. The ex-vivo assay showed higher IL-10 secretion in response to LPS immediately (p = 0.003) after both acute MICT and HIIT exercise sessions, independent of training period. Fifteen subjects presented decreased HOMA-IR after 6-weeks and seven presented an increase in this index. When we excluded the two least responsive subjects, it was possible to observe a decrease in HOMA-IR (p = 0.020) after training. Taken together, our results suggest that both HIIT and MICT (with same energy expenditure) promote similar effects on HOMA-IR and led to elevations in IL-10 production in LPS-stimulated whole blood, suggesting that leukocytes had an enhanced ability to secrete anti-inflammatory cytokines after the exercise bout. | - |
Descrição: dc.description | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | - |
Descrição: dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
Descrição: dc.description | Exercise and Immunometabolism Research Group Post graduation Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP) | - |
Descrição: dc.description | Physical Education Physiotherapy University Center of Maringa (UniCesumar) | - |
Descrição: dc.description | Department of Cell and Developmental Biology Institute of Biomedical Sciences University of São Paulo (USP) | - |
Descrição: dc.description | Department of Health Basic Science Federal University of Health Sciences of Porto Alegre (UFCSPA) | - |
Descrição: dc.description | Exercise and Immunometabolism Research Group Post graduation Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP) | - |
Descrição: dc.description | CAPES: 001 | - |
Descrição: dc.description | FAPESP: 2015/22402-9 | - |
Descrição: dc.description | FAPESP: 2016/16712-8 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Cytokine | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Aerobic training | - |
Palavras-chave: dc.subject | Anti-inflammatory | - |
Palavras-chave: dc.subject | Isoenergetic training | - |
Palavras-chave: dc.subject | Short-term training | - |
Título: dc.title | High- and moderate-intensity training modify LPS-induced ex-vivo interleukin-10 production in obese men in response to an acute exercise bout | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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