Physicochemical characterisation of fluorohectorite: Water dynamics and nanocarrier properties

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversity of Copenhagen-
Autor(es): dc.contributorLägerhyddsvägen 1-
Autor(es): dc.contributorNorwegian University of Science and Technology (NTNU)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorLund-
Autor(es): dc.contributorOak Ridge National Laboratory (ORNL)-
Autor(es): dc.contributorDeakin University-
Autor(es): dc.contributorInstitut Max von Laue - Paul Langevin-
Autor(es): dc.contributorRutherford Appleton Laboratory-
Autor(es): dc.contributorUniversity of Oxford-
Autor(es): dc.creatorLarsen, Simon R.-
Autor(es): dc.creatorMichels, Leander-
Autor(es): dc.creatordos Santos, Éverton C. [UNESP]-
Autor(es): dc.creatorBerg, Marcella C.-
Autor(es): dc.creatorGates, Will P.-
Autor(es): dc.creatorAldridge, Laurie P.-
Autor(es): dc.creatorSeydel, Tilo-
Autor(es): dc.creatorOllivier, Jacques-
Autor(es): dc.creatorTelling, Mark T.F.-
Autor(es): dc.creatorFossum, Jon Otto-
Autor(es): dc.creatorBordallo, Heloisa N.-
Data de aceite: dc.date.accessioned2022-02-22T00:26:36Z-
Data de disponibilização: dc.date.available2022-02-22T00:26:36Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-10-15-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.micromeso.2020.110512-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/199148-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/199148-
Descrição: dc.descriptionClay minerals such as fluorohectorite (FHt) have come into prominence as drug carrier systems due to their layered structure and excellent cation exchange capabilities. Water present in the interlayers of FHt is believed to facilitate the uptake of bio-active molecules in these systems, yet details of this interaction are not well understood. To shed light into this question, using quasi-elastic neutron scattering and the jump diffusion model, we determined the diffusion coefficients and the residence time of water in this synthetic smectite clay. We demonstrate how different interlayer cations (Li+, Na+ and Ni2+) and different hydration levels influenced water mobility in FHt. By means of the elastic window method and analysis of the thermal decomposition of samples with the drug Ciprofloxacin intercalated at pH 2 in LiFHt, we confirmed that the intercalation process removed most of the interlayer water previously present in the clay. Based on the Kissinger procedure, we also showed that thermal decomposition of the intercalated drug was activated at lower temperature. These findings are discussed in relation to the drug's shelf life and might aid in the selection of clay systems for use as nanocarrier.-
Descrição: dc.descriptionDanish Agency for Science and Higher Education-
Descrição: dc.descriptionCarlsbergfondet-
Descrição: dc.descriptionNorges Forskningsråd-
Descrição: dc.descriptionEuropean Regional Development Fund-
Descrição: dc.descriptionNiels Bohr Institute University of Copenhagen, Universitetsparken 5-
Descrição: dc.descriptionDepartment of Chemistry Uppsala University Lägerhyddsvägen 1-
Descrição: dc.descriptionDepartment of Physics Norwegian University of Science and Technology (NTNU)-
Descrição: dc.descriptionFaculdade de Ciências Universidade Estadual Paulista (UNESP)-
Descrição: dc.descriptionEuropean Neutron Source (ESS) Lund-
Descrição: dc.descriptionOak Ridge National Laboratory (ORNL), Oak Ridge-
Descrição: dc.descriptionInstitute for Frontier Materials Deakin University, Burwood, VIC-
Descrição: dc.descriptionInstitut Max von Laue - Paul Langevin, CS 20156-
Descrição: dc.descriptionISIS Facility Rutherford Appleton Laboratory-
Descrição: dc.descriptionDepartment of Materials University of Oxford, Parks Road-
Descrição: dc.descriptionFaculdade de Ciências Universidade Estadual Paulista (UNESP)-
Descrição: dc.descriptionCarlsbergfondet: 2013-01-0589-
Descrição: dc.descriptionNorges Forskningsråd: 228551/RTS-
Descrição: dc.descriptionEuropean Regional Development Fund: KU-019-
Descrição: dc.descriptionEuropean Regional Development Fund: KU-025-
Idioma: dc.languageen-
Relação: dc.relationMicroporous and Mesoporous Materials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectClay mineral-
Palavras-chave: dc.subjectDecomposition kinetics-
Palavras-chave: dc.subjectNanocarrier-
Palavras-chave: dc.subjectNeutron spectroscopy-
Palavras-chave: dc.subjectWater mobility-
Título: dc.titlePhysicochemical characterisation of fluorohectorite: Water dynamics and nanocarrier properties-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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