Profile of pro-inflammatory cytokines in colostrum of nursing mothers at the extremes of reproductive age

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUNOESTE-
Autor(es): dc.contributorUniversidade Federal da Fronteira Sul/UFFS-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorInstituto Adolfo Lutz-IAL/Presidente Prudente-
Autor(es): dc.contributorUniversidade Estadual de Maringá (UEM)-
Autor(es): dc.creatorde Jesus Ferrari, Denise Vasconcelos-
Autor(es): dc.creatorPolettini, Jossimara-
Autor(es): dc.creatorde Moraes, Lucas Lima-
Autor(es): dc.creatorde Campos, Letícia Aguiar-
Autor(es): dc.creatorda Silva, Márcia Guimarães [UNESP]-
Autor(es): dc.creatorSaeki, Erika Kushikawa-
Autor(es): dc.creatorMorceli, Glilciane-
Data de aceite: dc.date.accessioned2022-02-22T00:26:10Z-
Data de disponibilização: dc.date.available2022-02-22T00:26:10Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1371/journal.pone.0231882-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/199010-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/199010-
Descrição: dc.descriptionGestations at the extremes of reproductive age are characterized as high-risk pregnancies, conditions that might influence colostrum composition. This first milk secretion contains nutrients necessary for the development and immunity of the newborn; therefore, this study aims to compare adolescent and advanced maternal age mothers regarding sociodemographic, gestational, and perinatal characteristics and the colostrum levels of pro-inflammatory cytokines in these groups of study. This cross-sectional study has compared sociodemographic, gestational and perinatal data from adolescent mothers (between 10 and 24 years old) (n = 117), advanced maternal age mothers (over 35 years of age) (n = 39) and mothers considered a control group (25 to 34 years old) (n = 58). Additionally, colostrum samples were obtained from the studied and control group subjects by manual milking, between 48 and 72 hours postpartum, and the samples were analyzed for cytokine concentrations by enzyme-linked immunosorbent assay (ELISA). The majority of the studied mothers reported living a stable union, and 81.2% of the adolescent mothers did not carry out any paid activity. Mothers with advanced maternal age mainly delivered by cesarean section and presented a higher body mass index (BMI). Neonatal weight and Apgar score were not different between the groups. The concentrations of interleukin (IL)-1β and IL-6 were higher in the colostrum of mothers with advanced age compared to adolescent mothers, but did not differ from the control group. The concentrations of IL-8 and tumor necrosis factor alpha did not differ between the three groups. Therefore, our data demonstrated that maternal age influenced the sociodemographic and gestational characteristics as well as the composition of colostrum cytokines.-
Descrição: dc.descriptionMestrado em Ciências da Saúde-Universidade do Oeste Paulista UNOESTE-
Descrição: dc.descriptionUniversidade Federal da Fronteira Sul/UFFS Campus Passo Fundo-
Descrição: dc.descriptionFaculdade de Ciências da Saúde-Universidade do Oeste Paulista UNOESTE-
Descrição: dc.descriptionFaculdade de Medicina de Botucatu Universidade Estadual Paulista/UNESP-
Descrição: dc.descriptionInstituto Adolfo Lutz-IAL/Presidente Prudente-
Descrição: dc.descriptionUniversidade do Estado de Minas Gerais UEMG/Campus Passos-
Descrição: dc.descriptionFaculdade de Medicina de Botucatu Universidade Estadual Paulista/UNESP-
Idioma: dc.languageen-
Relação: dc.relationPLoS ONE-
???dc.source???: dc.sourceScopus-
Título: dc.titleProfile of pro-inflammatory cytokines in colostrum of nursing mothers at the extremes of reproductive age-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.