Bioglass-based scaffolds coated with silver nanoparticles: Synthesis, processing and antimicrobial activity

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Federal de São Paulo (UNIFESP)-
Autor(es): dc.contributorIFSP-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorITA-
Autor(es): dc.creatorOliveira, Rodrigo L. M. S.-
Autor(es): dc.creatorBarbosa, Lucas-
Autor(es): dc.creatorHurtado, Carolina R.-
Autor(es): dc.creatorRamos, Lucas de P. [UNESP]-
Autor(es): dc.creatorMontanheiro, Thaís L. A.-
Autor(es): dc.creatorOliveira, Luciane D. [UNESP]-
Autor(es): dc.creatorTada, Dayane B.-
Autor(es): dc.creatorTrichês, Eliandra de Sousa-
Data de aceite: dc.date.accessioned2022-02-22T00:26:07Z-
Data de disponibilização: dc.date.available2022-02-22T00:26:07Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/jbm.a.36996-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/198991-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/198991-
Descrição: dc.descriptionOver the past few years, several tridimensional synthetic bone grafts, known as scaffolds, are being developed to overcome the autologous grafts limitations. Among the materials used on the production of scaffolds, the 45S5 bioglass stands out due to its capacity of bonding to hard and soft tissues. Silver nanoparticles are well-known for their antimicrobial properties and their incorporation on the scaffold may promote its antimicrobial response, avoiding microorganism proliferation on the materials surface. This study proposes a simple way to coat 45S5 bioglass-based scaffolds with silver nanoparticles. The scaffolds were obtained by the sponge replication technique and the silver nanoparticles were incorporated by soaking under ultrasonic stirring. The antimicrobial activity of the scaffolds was analyzed against three different microbial strains: S. aureus, P. aeruginosa, and C. albicans. Due to the heat treatment during the scaffold production, the bioglass crystalized mainly in a sodium calcium silicate phase, forming a glass–ceramic scaffold. The silver nanoparticles were coated in a well-distributed manner throughout the scaffold, while avoiding their aggregation. The coated scaffold inhibited the growth of all the analyzed microorganism. Therefore, the use of ultrasonic stirring to coat the bioglass scaffold with silver nanoparticles showed to be an efficient way to promote its antimicrobial response.-
Descrição: dc.descriptionBioceramics Laboratory Science and Technology Institute UNIFESP-
Descrição: dc.descriptionNanomaterials and Nanotoxicology Laboratory Science and Technology Institute UNIFESP-
Descrição: dc.descriptionIFSP-
Descrição: dc.descriptionScience and Technology Institute UNESP-
Descrição: dc.descriptionPlasmas and Processes Laboratory ITA-
Descrição: dc.descriptionScience and Technology Institute UNESP-
Idioma: dc.languageen-
Relação: dc.relationJournal of Biomedical Materials Research - Part A-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subject45S5 bioglass-
Palavras-chave: dc.subjectantimicrobial scaffolds-
Palavras-chave: dc.subjectglass–ceramic-
Palavras-chave: dc.subjectsilver nanoparticles-
Palavras-chave: dc.subjectsponge replication technique-
Título: dc.titleBioglass-based scaffolds coated with silver nanoparticles: Synthesis, processing and antimicrobial activity-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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