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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Federal University of Health Sciences of Porto Alegre | - |
Autor(es): dc.contributor | Methodist University Center IPA | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.creator | Da Silva, Igor Martins | - |
Autor(es): dc.creator | Santos, Maeli Andressa | - |
Autor(es): dc.creator | Galvão, Simone Lunelli | - |
Autor(es): dc.creator | Dorneles, Gilson P. | - |
Autor(es): dc.creator | Lira, Fabio Santos [UNESP] | - |
Autor(es): dc.creator | Romão, Pedro R. T. | - |
Autor(es): dc.creator | Peres, Alessandra | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:25:53Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:25:53Z | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2019-12-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1139/apnm-2019-0700 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/198915 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/198915 | - |
Descrição: dc.description | The aim of this study was to evaluate the impact of high-intensity strength training (ST) or low-intensity strength training with bloodflowrestriction (ST-BFR) on monocyte subsets, the expression of C-C chemokine receptor 5 (CCR5), and CD16 on monocytes, and tumor necrosis factor alpha (TNF-α) production of overweight men. Thirty overweight men were randomly assigned to conventional ST or ST-BFR. Both groups performed exercises of knee extension and biceps curl with equal volume (3 sessions/week) over 8 weeks, and the peripheral frequency of monocytes (CD14+CD16−, classical monocytes; CD14+CD16+, intermediate monocytes; CD14−CD16+, nonclassical monocytes), the mean fluorescence intensity (MFI) of CCR5 and CD16 on CD14+ monocytes; and the production of TNF-α by lipopolysaccharide (LPS)-stimulated cells were quantified. Eight weeks of ST increased the frequency of CD14+CD16− monocytes (p = 0.04) and reduced the percentage of CD14−CD16+ (p = 0.02) and the production of TNF-α by LPS-stimulated cells (p = 0.03). The MFI of CD16 on CD14+ monocytes decreased after the ST intervention (p = 0.02). No difference in monocyte subsets, CCR5 or CD16 expression, and TNF-α production were identified after ST-BFR intervention (p > 0.05). The adoption of ST promotes anti-inflammatory effects on monocyte subsets of overweight men, but this effect was lost when BFR was adopted. Novelty • High-intensity strength training reduces the production of TNF-α and the peripheral frequency of CD16+ monocytes in overweight men. • Blood flow restriction method blunts the strength training adaptations on monocyte subsets and pro-inflammatory TNF-α production in overweight men. | - |
Descrição: dc.description | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | - |
Descrição: dc.description | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | - |
Descrição: dc.description | Laboratory of Cellular and Molecular Immunology Department of Health Basic Sciences Federal University of Health Sciences of Porto Alegre | - |
Descrição: dc.description | Research Center Methodist University Center IPA | - |
Descrição: dc.description | Exercise and Immunometabolism Research Group Department of Physical Education São Paulo State University (UNESP) | - |
Descrição: dc.description | Exercise and Immunometabolism Research Group Department of Physical Education São Paulo State University (UNESP) | - |
Descrição: dc.description | CAPES: CAPES-PNPD-23038007200/11-08 | - |
Formato: dc.format | 659-666 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Applied Physiology, Nutrition and Metabolism | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Cytokines | - |
Palavras-chave: dc.subject | Exercise immunology | - |
Palavras-chave: dc.subject | Inflammation | - |
Palavras-chave: dc.subject | Monocytes | - |
Palavras-chave: dc.subject | Overweight | - |
Palavras-chave: dc.subject | Strength exercise | - |
Palavras-chave: dc.subject | Tumor necrosis factor-alpha | - |
Palavras-chave: dc.subject | Vascular occlusion | - |
Título: dc.title | Blood flow restriction impairs the inflammatory adaptations of strength training in overweight men: A clinical randomized trial | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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