Standardization of a new non-invasive device for assessment of arterial stiffness in rats: Correlation with age-related arteries’ structure

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorFabricio, Mayara F. [UNESP]-
Autor(es): dc.creatorJordão, Maria T.-
Autor(es): dc.creatorMiotto, Danyelle S. [UNESP]-
Autor(es): dc.creatorRuiz, Thalles F.R. [UNESP]-
Autor(es): dc.creatorVicentini, Carlos A. [UNESP]-
Autor(es): dc.creatorLacchini, Silvia-
Autor(es): dc.creatorSantos, Carlos Ferreira-
Autor(es): dc.creatorMichelini, Lisete C.-
Autor(es): dc.creatorAmaral, Sandra L. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:25:35Z-
Data de disponibilização: dc.date.available2022-02-22T00:25:35Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.mex.2020.100901-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/198814-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/198814-
Descrição: dc.descriptionPulse wave velocity (PWV) has become a gold standard index to quantify the stiffness of the aorta and is a predictor of cardiovascular events. A recent paper compared the pOpmètreⓇ, a device for measuring the finger-toe PWV, with other techniques and demonstrated its accuracy and validity. However, human devices do not allow the advancement of our knowledge on conditioning mechanisms. Based on its human validation, a new device, pOpetⓇ 1.0 system was designed for estimation of PWV in small animals and this present study aimed to standardize the pOpetⓇ 1.0 for estimation of arterial stiffness in rats, and to confirm its liability and stability as well as the reproducibility of assessments. Therefore several precautions were taken into consideration like as the correct position of the animal and photodiodes according to manufacturers’ suggestions. Results indicated that estimation of PWV through the new pOpetⓇ 1.0 device exhibits good internal consistency, stability and objectivity in all tests performed between days and evaluators. Importantly, data suggest for the first time that this new device is able to detect changes in arterial stiffness that are conditioned by age and pressure-related arterial remodeling. • This new pOpetⓇ device is able to detect changes in vessel structure. • This new pOpetⓇ device exhibits good internal consistency, stability and objectivity in all tests performed • Correct position of the animal and photodiodes are crucial to obtain a very stable signal.-
Descrição: dc.descriptionJoint Graduate Program in Physiological Sciences PIPGCF UFSCar/UNESP-
Descrição: dc.descriptionDepartment of Physical Education São Paulo State University (UNESP) School of Sciences-
Descrição: dc.descriptionDepartment of Biological Sciences São Paulo State University (UNESP) School of Sciences-
Descrição: dc.descriptionDepartment of Physiology and Biophysics Biomedical Sciences Institute University of São Paulo (SP)-
Descrição: dc.descriptionDepartment of Anatomy Biomedical Sciences Institute University of São Paulo (SP)-
Descrição: dc.descriptionBauru School of Dentistry University of São Paulo-
Descrição: dc.descriptionJoint Graduate Program in Physiological Sciences PIPGCF UFSCar/UNESP-
Descrição: dc.descriptionDepartment of Physical Education São Paulo State University (UNESP) School of Sciences-
Descrição: dc.descriptionDepartment of Biological Sciences São Paulo State University (UNESP) School of Sciences-
Idioma: dc.languageen-
Relação: dc.relationMethodsX-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAging-
Palavras-chave: dc.subjectAorta-
Palavras-chave: dc.subjectCarotid-
Palavras-chave: dc.subjectCollagen deposition-
Palavras-chave: dc.subjectFemoral-
Palavras-chave: dc.subjectHypertension-
Palavras-chave: dc.subjectpOpetⓇ 1.0 system for small animals-
Palavras-chave: dc.subjectPulse wave velocity-
Título: dc.titleStandardization of a new non-invasive device for assessment of arterial stiffness in rats: Correlation with age-related arteries’ structure-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.