DNA damages induced by both endotoxin and exotoxin produced by cyanobacteria.

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorPamplona-Silva, Maria Tereza [UNESP]-
Autor(es): dc.creatorGonçalves, Letícia Cristina [UNESP]-
Autor(es): dc.creatorBittencourt-Oliveira, Maria do Carmo-
Autor(es): dc.creatorMarin-Morales, Maria Aparecida [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:25:25Z-
Data de disponibilização: dc.date.available2022-02-22T00:25:25Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-09-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.chemosphere.2020.126716-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/198743-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/198743-
Descrição: dc.descriptionCyanobacteria are prokaryotes involved in the contamination of aquatic environments since they release toxins that are highly potent and dangerous for living organisms. Prokaryotes produce endo and exotoxins, among others. Exotoxins are highly toxic, while endotoxins have milder toxic effects. The present study evaluated the cytotoxicogenetic potency of both toxins studying them in different concentrations of cyanobacterial biomasses (1 μg/L, 1.5 μg/L, 2 μg/L), to assess the amount of exotoxin present in the cultured medium in which the cyanobacteria were grown. For this evaluation, we used an extract taken from the medium in a concentration of 10%. Our results showed that genotoxic and mutagenic changes in Allium cepa could be observed in all of the varying concentrations of biomass (endotoxin action) and also in the medium induced with exotoxin. Even at low concentrations, these toxins were highly effective at triggering changes in the DNA molecules of organisms exposed to them. This information is highly significant when considering environmental contamination caused by cyanobacteria blooms, since the results of this study show that these toxins may not only kill organisms when found in high concentrations, but also induce mutations when found in low concentrations. Since these mutations are expressed later on in the organisms, it is impossible to associate the observed effect with the event that induced the damage.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionUNESP – Univ Estadual Paulista Departamento de Biologia Instituto de Biociências, Av 24-A, 1515, São Paulo-
Descrição: dc.descriptionDepartamento de Ciências Biológicas ESALQ Universidade de São Paulo, Av. Pádua Dias 11, São Paulo-
Descrição: dc.descriptionUNESP – Univ Estadual Paulista Departamento de Biologia Instituto de Biociências, Av 24-A, 1515, São Paulo-
Descrição: dc.descriptionCNPq: CNPq 460962/2014–0-
Idioma: dc.languageen-
Relação: dc.relationChemosphere-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAllium cepa-
Palavras-chave: dc.subjectBiomass-
Palavras-chave: dc.subjectChromosomal aberration-
Palavras-chave: dc.subjectCulture medium-
Palavras-chave: dc.subjectCyanotoxins-
Palavras-chave: dc.subjectMicronuclei-
Título: dc.titleDNA damages induced by both endotoxin and exotoxin produced by cyanobacteria.-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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