Parvalbumin and Ubiquitin as Potential Biomarkers of Mercury Contamination of Amazonian Brazilian Fish

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Federal de Mato Grosso do Sul (UFMS)-
Autor(es): dc.contributorUniversity of Nebraska-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorDom Bosco Catholic University (UCDB)-
Autor(es): dc.creatorVieira, José Cavalcante Souza [UNESP]-
Autor(es): dc.creatorde Oliveira, Grasieli [UNESP]-
Autor(es): dc.creatorBraga, Camila Pereira-
Autor(es): dc.creatorda Silva Fernandes, Mileni-
Autor(es): dc.creatorde Moraes, Paula Martin-
Autor(es): dc.creatorBuzalaf, Marília Afonso Rabelo-
Autor(es): dc.creatorde Oliveira, Lincoln Carlos Silva-
Autor(es): dc.creatorde Magalhães Padilha, Pedro [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:24:24Z-
Data de disponibilização: dc.date.available2022-02-22T00:24:24Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s12011-020-02026-w-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/198389-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/198389-
Descrição: dc.descriptionRecent studies have demonstrated the association of mercury (Hg) with some fish proteins, milk, and hair from individuals exposed to the element in the Amazon. However, few studies involve identifying biomarkers of mercury exposure. Therefore, the present study aimed to identify potential biomarkers of Hg exposure in fish. For this, the muscular tissues of two species of fish (Prochilodus lineatus and Mylossoma duriventre) that feed the Amazonian human population were analyzed. Through the analyses obtained by graphite furnace atomic absorption spectrometry (GFAAS), it was possible to identify four protein SPOTS where mercury was present. These SPOTS, identified by mass spectrometry (ESI-MS/MS), included parvalbumin and ubiquitin-40S ribosomal protein S27a, and these being metalloproteins with biomarker characteristics. In addition, the results show the intense Hg/protein ratio observed in the two proteins, which makes metalloproteins strong candidates for biomarkers of mercury exposure. [Figure not available: see fulltext.].-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Biosciences-
Descrição: dc.descriptionFederal University of Mato Grosso do Sul (UFMS)-
Descrição: dc.descriptionBiochemistry Department University of Nebraska-
Descrição: dc.descriptionUniversity of São Paulo (USP)-
Descrição: dc.descriptionLocal Development Dom Bosco Catholic University (UCDB)-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Biosciences-
Formato: dc.format667-675-
Idioma: dc.languageen-
Relação: dc.relationBiological Trace Element Research-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiomarkers-
Palavras-chave: dc.subjectFish-
Palavras-chave: dc.subjectMercury in the Amazon-
Palavras-chave: dc.subjectMercury-bound proteins-
Palavras-chave: dc.subjectMetalloproteins-
Palavras-chave: dc.subjectProteomics-
Título: dc.titleParvalbumin and Ubiquitin as Potential Biomarkers of Mercury Contamination of Amazonian Brazilian Fish-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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