Orange juice associated with a balanced diet mitigated risk factors of metabolic syndrome: A randomized controlled trial

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorPonce, Olivia [UNESP]-
Autor(es): dc.creatorBenassi, Renata [UNESP]-
Autor(es): dc.creatorCesar, Thais [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:23:29Z-
Data de disponibilização: dc.date.available2022-02-22T00:23:29Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2019-09-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jnim.2019.100101-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/198085-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/198085-
Descrição: dc.descriptionIn this 12 weeks randomized parallel controlled trial, we investigated whether the daily intake of orange juice (OJ) associated with a balanced diet attenuates risk factors in individuals with metabolic syndrome (MetS) and reverses this condition. Patients were divided into two groups: control (n = 36) and OJ (n = 36), which adopted a balanced diet according to the MetS guidelines. In addition, the OJ group consumed 500 mL/d OJ, maintaining the recommended dietary energy intake but adding more vitamin C (133%) and folic acid (43%) than controls. After the intervention, both groups showed a mean reduction of glucose (−3%), cholesterol (−7.5%), HDLC (−8%), BMI (−2%), waist circumference (−5.5%), and systolic and diastolic blood pressure (−8% and −9.5%, respectively). However, only the OJ group decreased insulin (−9%), insulin resistance (- 8%), LDL-C (−4%), CRP (−28%) and higher hsCRP levels (−61%), while the control group reduced exclusively triglycerides (−8.4%). Both groups showed a slight increase in antioxidant capacity (1%). The reversion of MetS to normality was similar in both groups: 12 out of 36 controls (33%) and 13 out of 36 subjects supplemented with OJ (36%). MetS reversal was due to a decrease in the risk factors, such as systolic pressure in the controls, and high glucose, insulin resistance, systemic inflammation and LDL-C, without altering HDL-C, in the OJ group. In conclusion, both treatments reduced risk factors and together reversed more than 30% MetS to normal, but the addition of OJ mitigated more risk factors than the balanced diet alone. (NCT 03301675).-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionNutrition Laboratory School of Pharmaceutical Sciences Sao Paulo State University - UNESP, Rodovia Araraquara-Jau km1-
Descrição: dc.descriptionNutrition Laboratory School of Pharmaceutical Sciences Sao Paulo State University - UNESP, Rodovia Araraquara-Jau km1-
Idioma: dc.languageen-
Relação: dc.relationJournal of Nutrition and Intermediary Metabolism-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBalanced diet-
Palavras-chave: dc.subjectGlycemia-
Palavras-chave: dc.subjectInflammation-
Palavras-chave: dc.subjectInsulin resistance-
Palavras-chave: dc.subjectMetabolic syndrome-
Palavras-chave: dc.subjectOrange juice-
Título: dc.titleOrange juice associated with a balanced diet mitigated risk factors of metabolic syndrome: A randomized controlled trial-
Tipo de arquivo: dc.typelivro digital-
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