Genome-wide association studies for growth traits in buffaloes using the single step genomic BLUP

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorInst Fed Goiano-
Autor(es): dc.contributorUniv Maryland-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorFundacao Univ Fed Grande Dourados-
Autor(es): dc.creatorAraujo Neto, Francisco Ribeiro de-
Autor(es): dc.creatorAbreu Santos, Daniel Jordan de-
Autor(es): dc.creatorFernandes Junior, Gerardo Alves [UNESP]-
Autor(es): dc.creatorAspilcueta-Borquis, Rusbel Raul [UNESP]-
Autor(es): dc.creatorNascimento, Andre Vieira do [UNESP]-
Autor(es): dc.creatorSeno, Leonardo de Oliveira-
Autor(es): dc.creatorTonhati, Humberto [UNESP]-
Autor(es): dc.creatorOliveira, Henrique Nunes de [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:14:01Z-
Data de disponibilização: dc.date.available2022-02-22T00:14:01Z-
Data de envio: dc.date.issued2020-12-10-
Data de envio: dc.date.issued2020-12-10-
Data de envio: dc.date.issued2019-10-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s13353-019-00528-5-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/197529-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/197529-
Descrição: dc.descriptionGrowth traits are important for the profitability of buffalo breeding systems, since in general, these animals are raised both for meat and milk. In this study, the single-step genomic BLUP method was employed to prospect the genomic regions' associated with weight at standard ages of 100, 210, 365, and 550 days in a buffalo population, aiming to identify genes with stronger expression for those characteristics. We found 6, 1, 2, and 5 SNPs significantly associated (p value < 10(-5)) with weight at 100, 210, 365, and 550 days of age, respectively, where those SNPs respectively explained 0.164, 0.040, 0.044, and 0.213% of the additive variance of each trait. SNP AX-85099682 (BBU24) was significant for weight at 100, 210, and 365 days, indicating the existence of a possible QTL affecting the initial growth rate of buffaloes. All told, eight genes (CBLB, TRNAG-UCC, GADD45B, LOC112583811, MGAT4C, KCNMA1, SLC5A2, and TGFB1I1) were identified as candidates for the growth traits of buffaloes. However, molecular and gene expression studies are necessary to validate these genes for subsequent use in programs for genetic improvement of the species.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionInst Fed Goiano, Campus Rio Verde, Rio Verde, Brazil-
Descrição: dc.descriptionUniv Maryland, College Pk, MD 20742 USA-
Descrição: dc.descriptionUniv Estadual Paulista, Campus Jaboticabal, Jaboticabal, SP, Brazil-
Descrição: dc.descriptionFundacao Univ Fed Grande Dourados, Dourados, MS, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Campus Jaboticabal, Jaboticabal, SP, Brazil-
Descrição: dc.descriptionCNPq: 420202/2016-1-
Descrição: dc.descriptionFAPESP: 2016/21213-0-
Formato: dc.format113-115-
Idioma: dc.languageen-
Publicador: dc.publisherSpringer-
Relação: dc.relationJournal Of Applied Genetics-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectAnimal breeding-
Palavras-chave: dc.subjectBubalus bubalis-
Palavras-chave: dc.subjectDevelopment-
Palavras-chave: dc.subjectGWAS-
Título: dc.titleGenome-wide association studies for growth traits in buffaloes using the single step genomic BLUP-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.