Effects of a four week detraining period on physical, metabolic, and inflammatory profiles of elderly women who regularly participate in a program of strength training

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorTechnol Fed Univ Parana-
Autor(es): dc.creatorCelestrin, Carolina P. [UNESP]-
Autor(es): dc.creatorRocha, Guilherme Z. [UNESP]-
Autor(es): dc.creatorStein, Angelica M. [UNESP]-
Autor(es): dc.creatorGuadagnini, Dioze-
Autor(es): dc.creatorTadelle, Rafael M. [UNESP]-
Autor(es): dc.creatorSaad, Mario J. A.-
Autor(es): dc.creatorOliveira, Alexandre G. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:11:39Z-
Data de disponibilização: dc.date.available2022-02-22T00:11:39Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-08-26-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1186/s11556-020-00244-8-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/197232-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/197232-
Descrição: dc.descriptionBackground Human aging has innumerable health implications, including loss of muscle mass and increased circulating inflammatory markers. Resistance exercise in the elderly can prevent muscle mass loss and improve the inflammatory profile. Conversely, detraining can reverse this picture. Thus, there is a strong need for studies with the elderly population to clarify the real impacts of a training interruption. Therefore, the objective of this study was to analyze the inflammatory profile of resistance trained elderly women after 4 weeks of detraining. Methods Seventeen elderly women with regular participation in an exercise program participated in the study. Body mass index (BMI), physical activity level assessments, total cholesterol and its fractions, triglycerides, glycemia and insulin blood levels, IL-1 beta, IL-4, IL-6, IL-10, IL-13, TNF-alpha, IFN gamma, and MCP-1 were assessed before and after the detraining protocol. Results The 4 week detraining period decreased physical fitness without altering body mass and BMI.The short detraining period was able to induce some metabolic disturbances in elderly women who regularly participate in a program of strength training, such as increasing HOMA-IR (0.72 +/- 0.14 to 0.81 +/- 0.23;p = 0.029), and increasing total blood cholesterol (178.21 +/- 23.64 to 220.90 +/- 64.98 mg/dL;p = 0.008) and LDL fraction (111.79 +/- 21.09 to 155.33 +/- 60.95 mg/dL;p = 0.048). No alteration in levels of inflammatory cytokines was observed, however, this detraining period significantly reduced IL-13 (44.84 +/- 100.85 to 35.84 +/- 78.89 pg/mL;p = 0.031) a Th2 cytokine that induces M2 macrophage polarization. Conclusions These data demonstrate that even a short period of detraining is harmful for elderly women who regularly participate in a program of strength training, since it impairs physical performance, insulin sensitivity and cholesterol metabolism.-
Descrição: dc.descriptionOCRC (Centro de Pesquisa em Obesidade e Comorbidades)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Biosci Inst, Dept Phys Educ, BR-13506900 Rio Claro, SP, Brazil-
Descrição: dc.descriptionUniv Estadual Campinas, Dept Internal Med, Campinas, Brazil-
Descrição: dc.descriptionTechnol Fed Univ Parana, Human Performance Res Grp, Curitiba, Parana, Brazil-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Biosci Inst, Dept Phys Educ, BR-13506900 Rio Claro, SP, Brazil-
Descrição: dc.descriptionOCRC (Centro de Pesquisa em Obesidade e Comorbidades): CEPID201307607-8-
Descrição: dc.descriptionCNPq: 573856/2008-7-
Descrição: dc.descriptionFAPESP: 2012/15009-0-
Formato: dc.format10-
Idioma: dc.languageen-
Publicador: dc.publisherSpringer-
Relação: dc.relationEuropean Review Of Aging And Physical Activity-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectAging-
Palavras-chave: dc.subjectInflammation-
Palavras-chave: dc.subjectPhysical exercise-
Título: dc.titleEffects of a four week detraining period on physical, metabolic, and inflammatory profiles of elderly women who regularly participate in a program of strength training-
Tipo de arquivo: dc.typelivro digital-
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