Antigen 5 Allergens of Hymenoptera Venoms and Their Role in Diagnosis and Therapy of Venom Allergy

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Autor(es): dc.contributorTech Univ Munich-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorPolytech Univ Marche-
Autor(es): dc.contributorJustus Liebig Univ Giessen-
Autor(es): dc.creatorBlank, Simon-
Autor(es): dc.creatorBazon, Murilo Luiz-
Autor(es): dc.creatorGrosch, Johannes-
Autor(es): dc.creatorSchmidt-Weber, Carsten B.-
Autor(es): dc.creatorBrochetto-Braga, Marcia Regina [UNESP]-
Autor(es): dc.creatorBilo, Maria Beatrice-
Autor(es): dc.creatorJakob, Thilo-
Data de aceite: dc.date.accessioned2022-02-22T00:11:18Z-
Data de disponibilização: dc.date.available2022-02-22T00:11:18Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-07-09-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s11882-020-00954-0-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/197108-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/197108-
Descrição: dc.descriptionPurpose of ReviewStings of Hymenoptera of the superfamily Vespoidea such as yellow jackets, paper wasps or stinging ants are common triggers for severe and even fatal allergic reactions. Antigen 5 allergens are potent allergens in the majority of these venoms with major importance for diagnosis and therapy. Reviewed here are the characteristics of antigen 5 allergens, their role in component-resolved diagnostics as well as current limitations of the available diagnostics for proper therapeutic decisions.Recent FindingsAntigens 5 are proteins of unknown function in Hymenoptera venoms with high allergenic potency. They represent key elements in component-resolved diagnosis to discriminate between honeybee and vespid venom allergy. However, due to their pronounced cross-reactivity, there are remaining diagnostic and therapeutic challenges that have to be addressed.SummaryAntigens 5 are highly relevant venom allergens of the Vespoidea superfamily. Although their use in component-resolved diagnosis facilitates dissection of cross-reactivity and primary allergy in double sensitization to honeybee and vespid venom, new diagnostic concepts are needed to discriminate between allergies to different vespid species.-
Descrição: dc.descriptionProjekt DEAL-
Descrição: dc.descriptionHelmholtz Association, Future Topic Immunology and Inflammation-
Descrição: dc.descriptionvon-Behring-Rontgen-Stiftung, Marburg-
Descrição: dc.descriptionUKGM-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionTech Univ Munich, German Res Ctr Environm Hlth, Sch Med, Ctr Allergy & Environm ZAUM, Ingolstadter Landstr 1, D-85764 Munich, Germany-
Descrição: dc.descriptionTech Univ Munich, German Res Ctr Environm Hlth, Helmholtz Ctr Munich, Ingolstadter Landstr 1, D-85764 Munich, Germany-
Descrição: dc.descriptionTech Univ Munich, German Ctr Lung Res DZL, Ingolstadter Landstr 1, D-85764 Munich, Germany-
Descrição: dc.descriptionSao Paulo State Univ, Biosci Inst, Dept Gen & Appl Biol, Rio Claro, SP, Brazil-
Descrição: dc.descriptionPolytech Univ Marche, Univ Hosp Ancona, Dept Internal Med, Dept Clin & Mol Sci,Ancona & Allergy Unit, Ancona, Italy-
Descrição: dc.descriptionJustus Liebig Univ Giessen, Dept Dermatol & Allergol, Expt Dermatol & Allergy Res Grp, Giessen, Germany-
Descrição: dc.descriptionSao Paulo State Univ, Biosci Inst, Dept Gen & Appl Biol, Rio Claro, SP, Brazil-
Descrição: dc.descriptionHelmholtz Association, Future Topic Immunology and Inflammation: ZT-0027-
Descrição: dc.descriptionvon-Behring-Rontgen-Stiftung, Marburg: NR66-0004-
Descrição: dc.descriptionUKGM: 7/2017GI-
Descrição: dc.descriptionFAPESP: 2019/02298-3-
Descrição: dc.descriptionFAPESP: 2017/07988-2-
Formato: dc.format13-
Idioma: dc.languageen-
Publicador: dc.publisherCurrent Medicine Group-
Relação: dc.relationCurrent Allergy And Asthma Reports-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectAntigen 5-
Palavras-chave: dc.subjectComponent-resolved diagnostics-
Palavras-chave: dc.subjectAllergen cross-reactivity-
Palavras-chave: dc.subjectHymenoptera venom allergy-
Palavras-chave: dc.subjectPolistes dominula venom-
Palavras-chave: dc.subjectYellow jacket venom-
Título: dc.titleAntigen 5 Allergens of Hymenoptera Venoms and Their Role in Diagnosis and Therapy of Venom Allergy-
Aparece nas coleções:Repositório Institucional - Unesp

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