Tissue microarrays of bone marrow aspirate clot allow assessment of multiple samples

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorDomeny-Duarte, Pollyanna [UNESP]-
Autor(es): dc.creatorNiero, Ligia [UNESP]-
Autor(es): dc.creatorCustodio Domingues, Maria Ap [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:10:21Z-
Data de disponibilização: dc.date.available2022-02-22T00:10:21Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.prp.2019.152721-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/196751-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/196751-
Descrição: dc.descriptionTime optimization and cost reduction without quality loss is fundamental for scientific production. The TMA technique allows large-scale analysis of paraffin-embedded and fixed tissues using non-decalcified bone marrow specimens. Cytoinclusion samples (n = 264) were selected from patients diagnosed with monoclonal gammopathy (n = 189) at Botucatu Medical School, Sao Paulo State University. Slides were cut from the TMA block and stained with H&E and immunohistochemical markers. Of the 276 fragments included in the receptor block, 45 core detachments were observed, thus 84% of the samples remained viable. The representative material allowed for adequate analysis of isolated cells, which showed nuclear, cytoplasmic and membrane staining. Thus, we verified that inclusion of bone marrow aspirate clot is a valid alternative for TMA histological and immunohistochemical analyses.-
Descrição: dc.descriptionSao Paulo State Univ, Botucatu Med Sch, Dept Pathol, BR-18618687 Botucatu, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Botucatu Med Sch, Dept Clin Med, BR-18618687 Botucatu, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Botucatu Med Sch, Dept Pathol, BR-18618687 Botucatu, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Botucatu Med Sch, Dept Clin Med, BR-18618687 Botucatu, SP, Brazil-
Formato: dc.format3-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier B.V.-
Relação: dc.relationPathology Research And Practice-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectTMA-
Palavras-chave: dc.subjectBone marrow clots-
Palavras-chave: dc.subjectImmunohistochemistry-
Título: dc.titleTissue microarrays of bone marrow aspirate clot allow assessment of multiple samples-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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