Evaluation of angiogenesis, inflammation, and healing on irradiated skin graft with low-level laser therapy in rats (Rattus norvegicus albinus wistar)

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorHosp Canc Barretos-
Autor(es): dc.creatorMoreira, Stella H. [UNESP]-
Autor(es): dc.creatorPazzini, Josiane M.-
Autor(es): dc.creatorAlvarez, Jorge L. G. [UNESP]-
Autor(es): dc.creatorCassino, Pedro C. [UNESP]-
Autor(es): dc.creatorBustamante, Caio C. [UNESP]-
Autor(es): dc.creatorBernardes, Filippo J. L. [UNESP]-
Autor(es): dc.creatorKajiura, Caroline Y. [UNESP]-
Autor(es): dc.creatorDe Nardi, Andrigo B. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:09:58Z-
Data de disponibilização: dc.date.available2022-02-22T00:09:58Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-02-14-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s10103-019-02917-y-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/196619-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/196619-
Descrição: dc.descriptionThe reconstructive techniques have been widely used in Veterinary Medicine. The post-operative adjuvants therapies like the low-level laser therapy (LLLT) are used to decrease inherent complications to reconstructive surgeries. This article purposed to define the LLLT effects on the healing, inflammation, and vascularization of the skin grafts in applicable time intervals to veterinary surgical routine. Forty rats (Rattus norvegicus albinus wistar) were used and each one was submitted to autogenous cutaneous mesh grafting in the interescapular region. The rats were randomly distributed in five groups (G1, G2, G3, G4, and G5) in accordance with the 6 J/cm(2) or 10 J/cm(2) dose every 3 or 5 days. These treatments were applied on the skin graft for 15 days. The histochemical evaluation with Picrosirius showed greater expression of collagen type 1 - red in grafts of G5 (p < 0.05), while in G1 did not; the expression of collagen type III - green was not induced by LLLT. The histochemical evaluation with hematoxylin-eosin showed greater numbers of fibroblasts in grafts of G4 (p < 0.05) and less hemorrhage in grafts of G5 (p < 0.05). There was modulation of the inflammatory response in irradiated skin grafts. It is concluded the exhibition of the skin grafts to 6 J/cm(2) or 10 J/cm(2) dose every 5 days improved the healing and the modulation of the local inflammation.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionUniv Estadual Paulista, Dept Clin & Cirurgia Vet, Jaboticabal, SP, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Dept Clin & Cirurgia Vet, Fac Ciencias Agr & Vet, Via Acesso Prof Paulo Donato Castellane S-N, BR-14884900 Jaboticabal, SP, Brazil-
Descrição: dc.descriptionHosp Canc Barretos, Ctr Pesquisa Oncol Mol, Barretos, SP, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Dept Clin & Cirurgia Vet, Jaboticabal, SP, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Dept Clin & Cirurgia Vet, Fac Ciencias Agr & Vet, Via Acesso Prof Paulo Donato Castellane S-N, BR-14884900 Jaboticabal, SP, Brazil-
Descrição: dc.descriptionFAPESP: 2017/25951-9-
Formato: dc.format1103-1109-
Idioma: dc.languageen-
Publicador: dc.publisherSpringer-
Relação: dc.relationLasers In Medical Science-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectPicrosirius-
Palavras-chave: dc.subjectLow-level laser therapy-
Palavras-chave: dc.subjectSkin graft-
Palavras-chave: dc.subjectCOX-2-
Palavras-chave: dc.subjectCD31-
Palavras-chave: dc.subjectHistology-
Título: dc.titleEvaluation of angiogenesis, inflammation, and healing on irradiated skin graft with low-level laser therapy in rats (Rattus norvegicus albinus wistar)-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.