PANEV: an R package for a pathway-based network visualization

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniv Molise-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniv Cattolica Sacro Cuore-
Autor(es): dc.contributorUniv Perugia-
Autor(es): dc.contributorUniv Udine-
Autor(es): dc.creatorPalombo, Valentino-
Autor(es): dc.creatorMilanesi, Marco [UNESP]-
Autor(es): dc.creatorSferra, Gabriella-
Autor(es): dc.creatorCapomaccio, Stefano-
Autor(es): dc.creatorSgorlon, Sandy-
Autor(es): dc.creatorD'Andrea, Mariasilvia-
Data de aceite: dc.date.accessioned2022-02-22T00:09:50Z-
Data de disponibilização: dc.date.available2022-02-22T00:09:50Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-02-05-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1186/s12859-020-3371-7-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/196569-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/196569-
Descrição: dc.descriptionBackground During the last decade, with the aim to solve the challenge of post-genomic and transcriptomic data mining, a plethora of tools have been developed to create, edit and analyze metabolic pathways. In particular, when a complex phenomenon is considered, the creation of a network of multiple interconnected pathways of interest could be useful to investigate the underlying biology and ultimately identify functional candidate genes affecting the trait under investigation. Results PANEV (PAthway NEtwork Visualizer) is an R package set for gene/pathway-based network visualization. Based on information available on KEGG, it visualizes genes within a network of multiple levels (from 1 to n) of interconnected upstream and downstream pathways. The network graph visualization helps to interpret functional profiles of a cluster of genes. Conclusions The suite has no species constraints and it is ready to analyze genomic or transcriptomic outcomes. Users need to supply the list of candidate genes, specify the target pathway(s) and the number of interconnected downstream and upstream pathways (levels) required for the investigation. The package is available at https://github.com/vpalombo/PANEV.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionUniv Molise, Dipartimento Agr Ambiente & Alimenti, I-86100 Campobasso, Italy-
Descrição: dc.descriptionSao Paulo State Univ, Sch Vet Med, Dept Support Prod & Anim Hlth, BR-16050680 Aracatuba, SP, Brazil-
Descrição: dc.descriptionUniv Cattolica Sacro Cuore, Ist Zootecn, I-29122 Piacenza, Italy-
Descrição: dc.descriptionUniv Molise, Dipartimento Biosci & Territorio, I-86090 Pesche, IS, Italy-
Descrição: dc.descriptionUniv Perugia, Dipartimento Med Vet, I-06126 Perugia, Italy-
Descrição: dc.descriptionUniv Udine, Dipartimento Sci Agr & Ambientali, I-33100 Udine, Italy-
Descrição: dc.descriptionSao Paulo State Univ, Sch Vet Med, Dept Support Prod & Anim Hlth, BR-16050680 Aracatuba, SP, Brazil-
Descrição: dc.descriptionFAPESP: 2016/05787-7-
Formato: dc.format7-
Idioma: dc.languageen-
Publicador: dc.publisherBmc-
Relação: dc.relationBmc Bioinformatics-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectMolecular pathways-
Palavras-chave: dc.subjectPathway visualization-
Palavras-chave: dc.subjectGenomic and transcriptomic analysis-
Palavras-chave: dc.subjectData mining-
Palavras-chave: dc.subjectKEGG-
Título: dc.titlePANEV: an R package for a pathway-based network visualization-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.