Lentinus edodes Exposure before and after Fetus Implantation: Materno-Fetal Development in Rats with Gestational Diabetes Mellitus

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniv Sorocaba-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorLaurino, Leticia F.-
Autor(es): dc.creatorViroel, Fabia J. M.-
Autor(es): dc.creatorCaetano, Erika-
Autor(es): dc.creatorSpim, Sara-
Autor(es): dc.creatorPickler, Thaisa B.-
Autor(es): dc.creatorRosa-Castro, Raquel M.-
Autor(es): dc.creatorVasconcelos, Edilma Albuquerque-
Autor(es): dc.creatorJozala, Angela F.-
Autor(es): dc.creatorHataka, Alessandre [UNESP]-
Autor(es): dc.creatorGrotto, Denise-
Autor(es): dc.creatorGerenutti, Marli-
Data de aceite: dc.date.accessioned2022-02-22T00:09:20Z-
Data de disponibilização: dc.date.available2022-02-22T00:09:20Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2019-10-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/nu11112720-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/196404-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/196404-
Descrição: dc.descriptionBackground: The presence of beta-glucans and phenolic compounds in Lentinus edodes suggests this mushroom can be used as a nutritional supplement. Two gestational conditions (before and after fetus implantation) were evaluated, and Lentinus edodes exposure was performed in diabetes mellitus rat model induced by streptozotocin in pre-clinical tests. Methods: On the 20th day of pregnancy, cesarean sections were performed. Blood was collected for biochemical, hematologic parameters and oxidative stress biomarkers. Placenta and amniotic fluid were collected, and fetuses were analyzed through morphological evaluation. Results: The mushroom did not reduce the severe hyperglycemia of the mother-concept but promoted an increase in maternal insulin levels; reduced the levels of alanine aminotransferase, and aspartate aminotransferase, triglyceride and total cholesterol; protected the animals from post-implantation losses. Liver damage induced by streptozotocin was reversed in experimental groups. Conclusions: Lentinus edodes mushroom has antioxidant properties that can minimize the damage caused by gestational diabetes mellitus.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionFinanciadora de Estudos e Projetos-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionUniv Sorocaba, BR-18023000 Sorocaba, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Sch Vet Med & Anim Sci, Dept Vet Clin Sci, BR-18610307 Botucatu, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Sch Vet Med & Anim Sci, Dept Vet Clin Sci, BR-18610307 Botucatu, SP, Brazil-
Descrição: dc.descriptionFAPESP: 2015/24566-9-
Descrição: dc.descriptionFAPESP: 2013/05765-5-
Descrição: dc.descriptionFinanciadora de Estudos e Projetos: FINEP-01.10.0659.00-
Formato: dc.format14-
Idioma: dc.languageen-
Publicador: dc.publisherMdpi-
Relação: dc.relationNutrients-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectLentinus edodes-
Palavras-chave: dc.subjectmushroom nutraceuticals-
Palavras-chave: dc.subjectgestational diabetes mellitus-
Palavras-chave: dc.subjectanti-diabetic activity-
Palavras-chave: dc.subjectpre-clinical study-
Título: dc.titleLentinus edodes Exposure before and after Fetus Implantation: Materno-Fetal Development in Rats with Gestational Diabetes Mellitus-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.