Blood flow distribution in embryonic common snapping turtles Chelydra serpentina (Reptilia; Chelonia) during acute hypoxia and alpha-adrenergic regulation

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniv North Texas-
Autor(es): dc.contributorUniv Birmingham-
Autor(es): dc.creatorSartori, Marina R. [UNESP]-
Autor(es): dc.creatorKohl, Zachary F.-
Autor(es): dc.creatorTaylor, Edwin W. [UNESP]-
Autor(es): dc.creatorAbe, Augusto S. [UNESP]-
Autor(es): dc.creatorCrossley, Dane A.-
Data de aceite: dc.date.accessioned2022-02-22T00:09:09Z-
Data de disponibilização: dc.date.available2022-02-22T00:09:09Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2019-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.cbpa.2019.110575-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/196332-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/196332-
Descrição: dc.descriptionEmbryonic turtles have four distinct vascular beds that separately perfuse the developing embryo's body and the extra-embryonic yolk sac, amnion and chorioallantoic membrane (CAM). The mechanisms enabling differential regulation of blood flow through these separate beds, in order to meet the varying demands of the embryo during development, is of current interest. The present investigation followed the changes in blood flow distribution during an acute exposure to hypoxia and after alpha-adrenergic blockade. We monitored heart rate (f(H)), mean arterial pressure (P-m), and determined relative blood flow distribution (%(Q) over dot sys) using colored microspheres. At 70% and 90% of the incubation period hypoxia elicited a bradycardia without changing P-m while %(Q) over dot sys was altered only at 70%, increasing to the CAM and liver. Blockade of alpha-adrenergic responses with phentolamine did not change f(H) or P-m but increased %(Q) over dot sys to the shell. These results show the capacity of embryos to redistribute cardiac output during acute hypoxia, however a-adrenergic receptors seemed to play a relatively small role in embryonic cardiovascular regulation.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionNational Science Foundation-
Descrição: dc.descriptionUniv Estadual Paulista, Inst Biociencias, Dept Zool, Campus Rio Claro, BR-13506900 Rio Claro, SP, Brazil-
Descrição: dc.descriptionUniv North Texas, Dept Biol Sci, Dev Integrat Biol Cluster, Denton, TX 76203 USA-
Descrição: dc.descriptionUniv Birmingham, Sch Biosci, Birmingham B15 2TT, W Midlands, England-
Descrição: dc.descriptionUniv Estadual Paulista, Inst Biociencias, Dept Zool, Campus Rio Claro, BR-13506900 Rio Claro, SP, Brazil-
Descrição: dc.descriptionFAPESP: 2014/01666-5-
Descrição: dc.descriptionFAPESP: 2012/06938-8-
Descrição: dc.descriptionCNPq: 401061/2014-0-
Descrição: dc.descriptionNational Science Foundation: NSF IBN-IOS 0845741-
Formato: dc.format5-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier B.V.-
Relação: dc.relationComparative Biochemistry And Physiology A-molecular & Integrative Physiology-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectCardiovascular-
Palavras-chave: dc.subjectCardiac output-
Palavras-chave: dc.subjectReptiles-
Palavras-chave: dc.subjectMicrospheres-
Título: dc.titleBlood flow distribution in embryonic common snapping turtles Chelydra serpentina (Reptilia; Chelonia) during acute hypoxia and alpha-adrenergic regulation-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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