Color normalization of faded H&E-stained histological images using spectral matching

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorFed Univ ABC-
Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorAzevedo Tosta, Thaina A.-
Autor(es): dc.creatorFaria, Paulo Rogerio de-
Autor(es): dc.creatorNeves, Leandro Alves [UNESP]-
Autor(es): dc.creatorNascimento, Marcelo Zanchetta do-
Data de aceite: dc.date.accessioned2022-02-22T00:08:42Z-
Data de disponibilização: dc.date.available2022-02-22T00:08:42Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2019-08-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.compbiomed.2019.103344-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/196181-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/196181-
Descrição: dc.descriptionHistological samples stained with hematoxylin-eosin (H&E) are commonly used by pathologists in cancer diagnoses. However, the preparation, digitization, and storage of tissue samples can lead to color variations that produce poor performance when using histological image processing techniques. Thus, normalization methods have been proposed to adjust the color of the image. This can be achieved through the use of a spectral matching technique, where it is first necessary to estimate the H&E representation and the stain concentration in the image pixels by means of the RGB model. This study presents an estimation method for H&E stain representation for the normalization of faded histological samples. This application has been explored only to a limited extent in the literature, but has the capacity to expand the use of faded samples. To achieve this, the normalized images must have a coherent color representation of the H&E stain with no introduction of noise, which was realized by applying the methodology described in this proposal. The estimation method presented here aims to normalize histological samples with different degrees of fading using a combination of fuzzy theory and the Cuckoo search algorithm, and dictionary learning with an initialization method for optimization. In visual and quantitative comparisons of estimates of H&E stain representation from the literature, our proposed method achieved very good results, with a high feature similarity between the original and normalized images.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)-
Descrição: dc.descriptionFed Univ ABC, Ctr Math Comp & Cognit, Av Estados 5001, BR-09210580 Santo Andre, SP, Brazil-
Descrição: dc.descriptionUniv Fed Uberlandia, Inst Biomed Sci, Dept Histol & Morphol, Av Amazonas S-N, BR-38405320 Uberlandia, MG, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Dept Comp Sci & Stat, R Cristovao Colombo 2265, BR-15054000 Sao Jose Do Rio Preto, SP, Brazil-
Descrição: dc.descriptionUniv Fed Uberlandia, Fac Comp Sci, Av Jodo Naves de Avila 2121, BR-38400902 Uberlandia, MG, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Dept Comp Sci & Stat, R Cristovao Colombo 2265, BR-15054000 Sao Jose Do Rio Preto, SP, Brazil-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionCNPq: 304848/2018-2-
Descrição: dc.descriptionCNPq: 430965/2018-4-
Descrição: dc.descriptionCNPq: 313365/2018-0-
Descrição: dc.descriptionFAPEMIG: APQ-00578-18-
Descrição: dc.descriptionCAPES: 1575210-
Formato: dc.format14-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier B.V.-
Relação: dc.relationComputers In Biology And Medicine-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectColor normalization-
Palavras-chave: dc.subjectHistological images-
Palavras-chave: dc.subjectFaded histological samples-
Palavras-chave: dc.subjectSpectral matching-
Título: dc.titleColor normalization of faded H&E-stained histological images using spectral matching-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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