Natural antibodies in paracoccidioidomycosis

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniv Taubate-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorUniversidade Federal de São Paulo (UNIFESP)-
Autor(es): dc.creatorUnterkircher, C. S.-
Autor(es): dc.creatorLeao, MVP-
Autor(es): dc.creatorBlotta, MHSL-
Autor(es): dc.creatorCamargo, Z. P. de-
Data de aceite: dc.date.accessioned2022-02-22T00:07:04Z-
Data de disponibilização: dc.date.available2022-02-22T00:07:04Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2004-01-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/195840-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/195840-
Descrição: dc.descriptionRecent attention has been focused oil the natural antibodies as a component of natural immunity and as integral part of the idiotypic network. However, their functional role in different infections has rarely been studied. This work was undertaken to investigate the presence of natural antibodies in paracoccidioidomycosis (PCM). In addition, we analyzed anti-P. brasiliensis antibodies and their distribution in IgG subclasses in order to acquire better knowledge about the humoral immune response in this mycosis. Our findings show that the natural antibody response is not very much increased in PCM when compared with other parasite infections and this response is restricted to a few specificities, suggesting that P. brasiliensis moderately triggers CD5+ B cells. The anti-actin antibody was the main antibody specificity found in PCM. Specific antibodies to P. brasiliensis were mainly found in the IgG1 subclass in chronic patients of PCM.-
Descrição: dc.descriptionUniv Estadual Paulista, Fac Odontol, Dept Biociencias & Diagnost Bucal, Sao Jose Dos Campos, Brazil-
Descrição: dc.descriptionUniv Taubate, Dept Med, Taubate, SP, Brazil-
Descrição: dc.descriptionUniv Estadual Campinas, Fac Ciencias Med, Dept Patol Clin, Campinas, SP, Brazil-
Descrição: dc.descriptionEscola Paulista Med, Disciplina Biol Celular, BR-04023 Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Fac Odontol, Dept Biociencias & Diagnost Bucal, Sao Jose Dos Campos, Brazil-
Formato: dc.format59-63-
Idioma: dc.languageen-
Publicador: dc.publisherSoc Brasileira Microbiologia-
Relação: dc.relationBrazilian Journal Of Microbiology-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectnatural antibodies-
Palavras-chave: dc.subjectParacoccidioides brasiliensis-
Palavras-chave: dc.subjectparacoccidioidomycosis-
Título: dc.titleNatural antibodies in paracoccidioidomycosis-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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