Potentiometric determination of captopril in pharmaceutical formulations

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorRibeiro, PRD-
Autor(es): dc.creatorSantini, A. O.-
Autor(es): dc.creatorPezza, H. R.-
Autor(es): dc.creatorPezza, L.-
Data de aceite: dc.date.accessioned2022-02-22T00:06:47Z-
Data de disponibilização: dc.date.available2022-02-22T00:06:47Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2003-01-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/195747-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/195747-
Descrição: dc.descriptionA simple, precise, rapid and low-cost potentiometric method for captopril determination in pure form and in pharmaceutical preparations is proposed. Captopril present in tablets containing known quantity of drug was potentiometrically titrated in aqueous solution with NaOH using a glass pH electrode, coupled to an autotitrator. No interferences were observed in the presence of common components of the tablets as lactose, microcrystalline cellulose, croscarmellose sodium, starch and magnesium stearate. The analytical results obtained by applying the proposed method compared very favorably with those obtained by the United States Pharmacopoeia Standard procedure. Recovery of captopril from various tablet dosage formulations range from 98.0 to 102.0%.-
Descrição: dc.descriptionUNESP, Inst Quim, Dept Quim Analit, BR-14801970 Araraquara, SP, Brazil-
Descrição: dc.descriptionUNESP, Inst Quim, Dept Quim Organ, BR-14801970 Araraquara, SP, Brazil-
Descrição: dc.descriptionUNESP, Inst Quim, Dept Quim Analit, BR-14801970 Araraquara, SP, Brazil-
Descrição: dc.descriptionUNESP, Inst Quim, Dept Quim Organ, BR-14801970 Araraquara, SP, Brazil-
Formato: dc.format39-44-
Idioma: dc.languageen-
Publicador: dc.publisherEditora Unesp-
Relação: dc.relationEcletica Quimica-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectpotentiometric determination-
Palavras-chave: dc.subjectcaptopril-
Palavras-chave: dc.subjectpharmaceutical formulations-
Título: dc.titlePotentiometric determination of captopril in pharmaceutical formulations-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.