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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Barretos Canc Hosp | - |
Autor(es): dc.contributor | Univ Minho | - |
Autor(es): dc.contributor | ICVS 3Bs PT Govt Associate Lab | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.creator | Dias, Tauana Christina | - |
Autor(es): dc.creator | Longatto-Filho, Adhemar | - |
Autor(es): dc.creator | Campanella, Nathalia C. | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:06:14Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:06:14Z | - |
Data de envio: dc.date.issued | 2020-12-09 | - |
Data de envio: dc.date.issued | 2020-12-09 | - |
Data de envio: dc.date.issued | 2020-07-30 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.2144/fsoa-2019-0159 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/195579 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/195579 | - |
Descrição: dc.description | The biological importance of human papillomavirus (HPV) in the field of medicine - related to cervical carcinogenesis - has been extensively reported in the last decades. For the first time, a direct correlation between cause and effect to explain a cancer development was completely achieved in medical research. Consequently, the Nobel Prize was awarded to HZ Hausen in 2008 for his efforts to understand the effects of persistent infection of oncogenic types of HPV and malignancy transformation. The aim of the present review was to summarize the principal elements of HPV characteristics and their importance in oncology. Lay abstract: It is established that HPV is the main etiologic agent for the development of cervical cancer. With the evolution of diagnosis and molecular biology, many tools have become essential for an early diagnosis and thereby, considerably reducing mortality. Molecular biology continues to advance and provide new perspectives with the use of reverse-transcription PCR in automation and genotyping through next-generation sequencing. This article aims to provide an overview of what is currently used in HPV diagnostic and research and future perspectives with the help of technologies such as next-generation sequencing for screening and vaccination. | - |
Descrição: dc.description | Barretos Canc Hosp, Mol Oncol Res Ctr, Sao Paulo, Brazil | - |
Descrição: dc.description | Univ Minho, Sch Hlth Sci, Life & Hlth Sci Res Inst ICVS, Braga, Portugal | - |
Descrição: dc.description | ICVS 3Bs PT Govt Associate Lab, Braga, Portugal | - |
Descrição: dc.description | Sao Paulo State Univ, Fac Med, Lab Med Invest LIM 14, Sao Paulo, Brazil | - |
Descrição: dc.description | Sao Paulo State Univ, Fac Med, Lab Med Invest LIM 14, Sao Paulo, Brazil | - |
Formato: dc.format | 8 | - |
Idioma: dc.language | en | - |
Publicador: dc.publisher | Future Sci Ltd | - |
Relação: dc.relation | Future Science Oa | - |
???dc.source???: dc.source | Web of Science | - |
Palavras-chave: dc.subject | cervical cancer | - |
Palavras-chave: dc.subject | E6 | - |
Palavras-chave: dc.subject | E7 | - |
Palavras-chave: dc.subject | HPV | - |
Palavras-chave: dc.subject | immunization | - |
Palavras-chave: dc.subject | NGS | - |
Palavras-chave: dc.subject | RT-PCR | - |
Título: dc.title | Human papillomavirus genotyping as a tool for cervical cancer prevention: from commercially available human papillomavirus DNA test to next-generation sequencing | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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