Antivirals Against Chikungunya Virus: Is the Solution in Nature?

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorSilva Martins, Daniel Oliveira [UNESP]-
Autor(es): dc.creatorSantos, Igor de Andrade-
Autor(es): dc.creatorOliveira, Debora Moraes de-
Autor(es): dc.creatorGrosche, Victoria Riquena-
Autor(es): dc.creatorGomes Jardim, Ana Carolina [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:05:26Z-
Data de disponibilização: dc.date.available2022-02-22T00:05:26Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/v12030272-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/195302-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/195302-
Descrição: dc.descriptionThe worldwide outbreaks of the chikungunya virus (CHIKV) in the last years demonstrated the need for studies to screen antivirals against CHIKV. The virus was first isolated in Tanzania in 1952 and was responsible for outbreaks in Africa and Southwest Asia in subsequent years. Between 2007 and 2014, some cases were documented in Europe and America. The infection is associated with low rates of death; however, it can progress to a chronic disease characterized by severe arthralgias in infected patients. This infection is also associated with Guillain-Barre syndrome. There is no specific antivirus against CHIKV. Treatment of infected patients is palliative and based on analgesics and non-steroidal anti-inflammatory drugs to reduce arthralgias. Several natural molecules have been described as antiviruses against viruses such as dengue, yellow fever, hepatitis C, and influenza. This review aims to summarize the natural compounds that have demonstrated antiviral activity against chikungunya virus in vitro.-
Descrição: dc.descriptionRoyal Society Newton Advanced Fellowship-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionUniv Fed Uberlandia, Inst Biomed Sci, Lab Virol, ICBIM, BR-38408100 Uberlandia, MG, Brazil-
Descrição: dc.descriptionState Univ Sao Paulo, Sao Paulo State Univ, Inst Biosci Letters & Exact Sci IBILCE, BR-15054000 Sao Jose Do Rio Preto, SP, Brazil-
Descrição: dc.descriptionState Univ Sao Paulo, Sao Paulo State Univ, Inst Biosci Letters & Exact Sci IBILCE, BR-15054000 Sao Jose Do Rio Preto, SP, Brazil-
Descrição: dc.descriptionRoyal Society Newton Advanced Fellowship: NA 150195-
Descrição: dc.descriptionCNPq: 445021/2014-4-
Descrição: dc.descriptionFAPEMIG: APQ-00587-14-
Descrição: dc.descriptionFAPEMIG: SICONV 793988/2013-
Descrição: dc.descriptionFAPEMIG: APQ-03385-18-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionCNPq: 311219/2019-5-
Formato: dc.format17-
Idioma: dc.languageen-
Publicador: dc.publisherMdpi-
Relação: dc.relationViruses-basel-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectchikungunya virus-
Palavras-chave: dc.subjectantiviral-
Palavras-chave: dc.subjectnatural compounds-
Título: dc.titleAntivirals Against Chikungunya Virus: Is the Solution in Nature?-
Aparece nas coleções:Repositório Institucional - Unesp

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