A simple procedure to obtain nanodiamonds from leftover of HFCVD system for biological application

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorFed Inst Sao Paulo IFSP-
Autor(es): dc.contributorNatl Inst Space Res INPE-
Autor(es): dc.contributorInst Aeronaut & Space IAE-
Autor(es): dc.contributorTechnol Inst Aerocaut ITA-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorHurtado, Carolina Ramos-
Autor(es): dc.creatorWachesk, Cristiane da Costa-
Autor(es): dc.creatorQueiroz, Rafaela Campos-
Autor(es): dc.creatorMacedo, Erenilda Ferreira de-
Autor(es): dc.creatorBorja de Oliveira Correia, Rebeca Falcao-
Autor(es): dc.creatorTaiariol, Thalita Sani-
Autor(es): dc.creatorDiniz, Milton Faria-
Autor(es): dc.creatorIsaias dos Santos, Alexandre Martins-
Autor(es): dc.creatorAmaral Montanheiro, Thais Larissa do-
Autor(es): dc.creatorHurtado, Gabriela Ramos [UNESP]-
Autor(es): dc.creatorTrava-Airoldi, Vladimir Jesus-
Autor(es): dc.creatorTada, Dayane Batista-
Data de aceite: dc.date.accessioned2022-02-22T00:05:14Z-
Data de disponibilização: dc.date.available2022-02-22T00:05:14Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s42452-020-1967-1-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/195229-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/195229-
Descrição: dc.descriptionNanodiamonds (NDs) are amongst the most investigated carbon-based nanostructures due to their chemical stability and favorable mechanical properties. Despite the number of works on methods for NDs production, one of the main challenges is to achieve their colloidal stability in aqueous suspension. Additionally, NDs are normally obtained by expensive, complex and time-consuming process. Herein, it was presented a facile method to obtain NDs in aqueous suspension by using columnar structure diamond from Hot-Filament Chemical Vapour Deposition reactor (HFCVD). CVD diamond leftover thick film from CVDVale Company was used. Therefore, this method has the advantage of being not only practical but also cost-effective since it brings a profitable use of CVD diamond leftover. The Diamond thick film was submitted to ultrasonic cavitation in the presence and absence of ZrO2 microbeads in aqueous medium. The NDs hydrodynamic diameter and the stability in aqueous suspension were monitored by light scattering, size and morphology were analyzed by transmission electronic microscopy. Considering the wide application of NDs in biomedical devices, cytotoxicity of aqueous suspensions of NDs was evaluated against murine embryonic fibroblast cells. Furthermore, NDs were functionalized with hydrogen and carboxyl groups. NDs aqueous suspension of straight size distribution was obtained even in the absence of ZrO2 beads, indicating that they may be dispensable in order to decrease NDs size. NDs of average hydrodynamic diameter of 22 nm and -35 mV of Zeta-potential were obtained after ultrasonic cavitation followed by 2 h of centrifugation, not demonstrating cytotoxicity to cells at very low (0.05-0.5 mu g/mL) nor at higher concentrations (116 mu g/mL). Nevertheless, NDs showed a moderate cytotoxicity at intermediary concentration range (0.5-2.2 mu g/mL). From our knowledge, this is the first work that reports on a facile method for providing NDs aqueous suspension with high colloidal stability from HFCVD diamond leftover.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionFed Univ Sao Paulo UNIFESP, Inst Sci & Technol, Nanomat & Nanotoxicol Lab, Talim 330, BR-12231280 Sao Jose Dos Campos, SP, Brazil-
Descrição: dc.descriptionFed Inst Sao Paulo IFSP, Rod Pres Dutra,Km 145, BR-12223201 Sao Jose Dos Campos, SP, Brazil-
Descrição: dc.descriptionNatl Inst Space Res INPE, Sensors & Mat Associated Lab, Av Astronautas 1-758, BR-12227010 Sao Jose Dos Campos, SP, Brazil-
Descrição: dc.descriptionInst Aeronaut & Space IAE, Aerosp Sci & Technol Dept, Praca Marechal Eduardo Gomes 50, BR-12228900 Sao Jose Dos Campos, SP, Brazil-
Descrição: dc.descriptionTechnol Inst Aerocaut ITA, Fundamental Sci Div, Praca Marechal Eduardo Gomes 50, BR-12228900 Sao Jose Dos Campos, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Inst Sci & Technol, Rod Pres Dutra,Km 137,8 Eugenio Melo, BR-12247004 Sao Jose Dos Campos, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Inst Sci & Technol, Rod Pres Dutra,Km 137,8 Eugenio Melo, BR-12247004 Sao Jose Dos Campos, SP, Brazil-
Descrição: dc.descriptionFAPESP: 2017/01697-6-
Descrição: dc.descriptionFAPESP: 2012/15857-1-
Formato: dc.format14-
Idioma: dc.languageen-
Publicador: dc.publisherSpringer-
Relação: dc.relationSn Applied Sciences-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectNanodiannonds-
Palavras-chave: dc.subjectUltrasonic cavitation-
Palavras-chave: dc.subjectCVD diamond-
Palavras-chave: dc.subjectFunctionalization-
Palavras-chave: dc.subjectCytotoxicity-
Palavras-chave: dc.subjectColloidal suspension-
Título: dc.titleA simple procedure to obtain nanodiamonds from leftover of HFCVD system for biological application-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.