Luminescent nanohybrids based on silica and silylated Ru(II)-Yb(III) heterobinuclear complex: new tools for biological media analysis

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorCIRIMAT Univ Toulouse-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorSabio, Rafael Miguel [UNESP]-
Autor(es): dc.creatorSantagneli, Silvia Helena [UNESP]-
Autor(es): dc.creatorGressier, Marie-
Autor(es): dc.creatorAlmeida Caiut, Jose Mauricio-
Autor(es): dc.creatorPazin, Wallance Moreira-
Autor(es): dc.creatorLeite, Ilaiali Souza-
Autor(es): dc.creatorInada, Natalia Mayumi-
Autor(es): dc.creatorSilva, Robson Rosa da-
Autor(es): dc.creatorLima Ribeiro, Sidney Jose [UNESP]-
Autor(es): dc.creatorMenu, Marie-Joelle-
Data de aceite: dc.date.accessioned2022-02-22T00:05:11Z-
Data de disponibilização: dc.date.available2022-02-22T00:05:11Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-02-13-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1088/1361-6528/ab55c3-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/195213-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/195213-
Descrição: dc.descriptionLanthanide (Ln) complexes emitting in the near-infrared (NIR) region have fostered great interest as upcoming optical tags owing to their high spatial and temporal resolution emission as well deeper light penetration in biological tissues for non-invasive monitoring. For use in live-cell imaging, lanthanide complexes with long-wavelength absorption and good brightness are especially critical. Light-harvesting ligands of Ln complexes are typically excited in the ultraviolet region, which in turn trigger simultaneously autofluorescence and long-exposition damage of living systems. The association of d-metalloligands rather than organic chromophores enables the excitation of NIR-emitting Ln complex occurs in the visible region. Taking advantage of the long-lived excited states and intense absorption band in the ultraviolet (UV) to NIR region of Ru(II), we successfully design a dual-emitting (in the visible and NIR region) d-f heterobinuclear complex based on Ru(II) metalloligand and Yb(III) complex. In addition, we developed luminescent nanohybrids by grafting of Ru(II)-Yb(III) heterobinuclear complexes containing silylated ligands on the surface of mesoporous and dense silica matrix. The nanomarkers were successfully applied for imaging of murine melanoma B16-F10 and neonatal human dermal fibroblast HDFn cell cultures by one-photon or two-photon absorption using laser scanning confocal microscopy. Great cellular uptake, low cytotoxicity and the possibility to achieve visible and NIR emission via two-photons excitation show that the nanohybrids are remarkable markers for in vitro and a potential tool for in vivo applications.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Inst Chem, Araraquara, SP, Brazil-
Descrição: dc.descriptionCIRIMAT Univ Toulouse, CNRS, UPS, INPT, 118 Route Narbonne, F-31062 Toulouse 9, France-
Descrição: dc.descriptionUniv Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Quim, BR-14040901 Ribeirao Preto, SP, Brazil-
Descrição: dc.descriptionUniv Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Fis, BR-14040901 Ribeirao Preto, SP, Brazil-
Descrição: dc.descriptionUniv Sao Paulo, Sao Carlos Inst Phys, Sao Carlos, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Inst Chem, Araraquara, SP, Brazil-
Formato: dc.format13-
Idioma: dc.languageen-
Publicador: dc.publisherIop Publishing Ltd-
Relação: dc.relationNanotechnology-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectsilylated d-f heterobinuclear complexes-
Palavras-chave: dc.subjectgrafting trialkoxysilyl group-
Palavras-chave: dc.subjectmesoporous silica nanoparticles-
Palavras-chave: dc.subjectvisible and NIR luminescent nanohybrids-
Palavras-chave: dc.subjectluminescent nanomarkers-
Título: dc.titleLuminescent nanohybrids based on silica and silylated Ru(II)-Yb(III) heterobinuclear complex: new tools for biological media analysis-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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