Spleen melanomacrophage centers response of Nile tilapia during Aeromanas hydrophila and Mycobacterium marinum infections

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorFed Univ Rondonia-
Autor(es): dc.contributorBrasil Univ-
Autor(es): dc.contributorBiol Inst Sao Paulo-
Autor(es): dc.creatorManrique, Wilson Gomez [UNESP]-
Autor(es): dc.creatorPereira Figueiredo, Mayra Araguaia-
Autor(es): dc.creatorCharlie-Silva, Ives-
Autor(es): dc.creatorAndrade Belo, Marco Antonio de [UNESP]-
Autor(es): dc.creatorDib, Cristina Corsi-
Data de aceite: dc.date.accessioned2022-02-22T00:04:40Z-
Data de disponibilização: dc.date.available2022-02-22T00:04:40Z-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2020-12-09-
Data de envio: dc.date.issued2019-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.fsi.2019.10.071-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/195055-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/195055-
Descrição: dc.descriptionIn order to understand the pathophysiology of melanomcrophage centers (MMCs) formation during the tilapia defense response to bacterial infections, the present study evaluated the response, in terms of area, number and pigment constitution, of splenic MMCs of Oreochromis niloticus subjected to intraperitoneal (i.p.) infection with Aeromonas hydrophila and Mycobacterium marinum. Eighty-four fish (396.9 +/- 21.0 g) were randomly distributed into twelve plastic tanks (300 L), to constitute three treatments with 28 animals each: control group (inoculated with PBS); Infected with A. hydrophila (1 x 10(7) UFC mL(-1)); Infected with M. marinum (1 x 10(6) UFC mL(-1)). The spleen was collected in seven fish per treatment on the 3rd, 7th, 14th and 21st day post-infection (DPI). The results revealed the participation of MMCs in the defense response of tilapia during bacterial infection by A. hydrophila and M. marinum, since there was an increase in the number and size of these cell aggregates. Variation of pigment accumulation with significant increase of hemosiderin, in infected tilapias by A. hydrophila, bacteria responsible for causing hemolytic anemia in fish was also found. On the other hand, M. marinum-infected tilapia had high amount of melanin in MMCs. In general, mycobacterial infections are notoriously difficult to treat, being characterized as a chronic disease. These findings demonstrate different strategies of fish response during the evolution of these bacterial diseases.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionSao Paulo State Univ, Jaboticabal Campus, Sao Paulo, SP, Brazil-
Descrição: dc.descriptionFed Univ Rondonia, Dept Vet Med, Rolim de Moura Campus, Rolim De Moura, Rondonia, Brazil-
Descrição: dc.descriptionBrasil Univ, Sao Paulo, SP, Brazil-
Descrição: dc.descriptionBiol Inst Sao Paulo, TB Lab, Sao Paulo, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Jaboticabal Campus, Sao Paulo, SP, Brazil-
Descrição: dc.descriptionFAPESP: 13/01838-8-
Formato: dc.format514-518-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier B.V.-
Relação: dc.relationFish & Shellfish Immunology-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectCichlids-
Palavras-chave: dc.subjectHemosiderin-
Palavras-chave: dc.subjectImmunity-
Palavras-chave: dc.subjectLipofuscin-
Palavras-chave: dc.subjectMelanin-
Palavras-chave: dc.subjectOreochromis niloticus-
Título: dc.titleSpleen melanomacrophage centers response of Nile tilapia during Aeromanas hydrophila and Mycobacterium marinum infections-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.