A Critical Review of the Properties and Analytical Methods for the Determination of Curcumin in Biological and Pharmaceutical Matrices

Registro completo de metadados
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorCarolina Alves, Renata-
Autor(es): dc.creatorPerosa Fernandes, Richard-
Autor(es): dc.creatorFonseca-Santos, Bruno-
Autor(es): dc.creatorDamiani Victorelli, Francesca-
Autor(es): dc.creatorChorilli, Marlus-
Data de aceite: dc.date.accessioned2021-03-11T01:39:49Z-
Data de disponibilização: dc.date.available2021-03-11T01:39:49Z-
Data de envio: dc.date.issued2019-10-06-
Data de envio: dc.date.issued2019-10-06-
Data de envio: dc.date.issued2019-03-04-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1080/10408347.2018.1489216-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/189761-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/189761-
Descrição: dc.descriptionCurcumin, a natural compound extracted from turmeric (Curcuma longa), has been extensively studied because of its various pharmacological properties, such as anti-inflammatory, antioxidant, antibiotic, antiprotozoal, immunomodulatory, anti-proliferative, antitumor, and anticarcinogenic effects. However, low solubility in aqueous media has limited its therapeutic applications. To overcome these bioavailability issues, the use of drug delivery systems providing localized or targeted delivery of this drug may represent a more viable therapeutic option. Several drug delivery systems have been shown to significantly enhance the therapeutic efficacy of curcumin. Additionally, a wide variety of analytical methods are available for the qualitative and quantitative analysis of curcumin in different matrices, including plant extracts, biological fluids, and drug delivery systems. There are a variety of methodologies to quantify curcumin, but chromatographic and spectroscopic techniques are the ones most commonly used. Thus, in this review, we evaluate the biological properties of curcumin, as well as its nanotechnology-based delivery systems and methods of analysis.-
Formato: dc.format138-149-
Idioma: dc.languageen-
Relação: dc.relationCritical Reviews in Analytical Chemistry-
Direitos: dc.rightsopenAccess-
Palavras-chave: dc.subjectAnalytical methods-
Palavras-chave: dc.subjectcurcumin-
Palavras-chave: dc.subjectdrug delivery systems-
Palavras-chave: dc.subjecthigh-performance liquid chromatography-
Palavras-chave: dc.subjectnanotechnology-
Título: dc.titleA Critical Review of the Properties and Analytical Methods for the Determination of Curcumin in Biological and Pharmaceutical Matrices-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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