Preoperative vitamin D level as a post-total thyroidectomy hypocalcemia predictor: a prospective study

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorSoares, Carlos Segundo Paiva-
Autor(es): dc.creatorTagliarini, José Vicente-
Autor(es): dc.creatorMazeto, Gláucia M.F.S.-
Data de aceite: dc.date.accessioned2021-03-11T01:39:17Z-
Data de disponibilização: dc.date.available2021-03-11T01:39:17Z-
Data de envio: dc.date.issued2019-10-06-
Data de envio: dc.date.issued2019-10-06-
Data de envio: dc.date.issued2019-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.bjorl.2019.07.001-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/189582-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/189582-
Descrição: dc.descriptionIntroduction: Hypocalcemia is one of the most common complications after total thyroidectomy. Preoperative serum vitamin D concentration has been postulated as a risk factor for this complication. However, the subject is still controversial and the role of vitamin D in the occurrence of hypocalcemia remains uncertain. Objective: To evaluate the capability of preoperative vitamin D concentrations in predicting post-total thyroidectomy hypocalcemia. Methods: Forty-seven total thyroidectomy patients were prospectively evaluated for serum 25(OH) vitamin D, calcium and parathyroid hormone before surgery, Calcium every 6 h, and parathyroid hormone 8 h post-operatively. Patients were divided according to postoperative corrected calcium into groups without (corrected calcium ≥8.5 mg/dL) and with hypocalcemia (corrected calcium <8.5 mg/dL), who were then evaluated for preoperative 25(OH) vitamin D values. Results: A total of 72.3% of cases presented altered 25(OH) vitamin D preoperative serum concentrations and 51% evolved with postoperative hypocalcemia. The with and without hypocalcemia groups did not differ for preoperative 25(OH) vitamin D (p = 0.62). Univariate analysis showed that age (p = 0.03), postoperative PTH concentration (p = 0.02), and anatomopathological diagnosis of malignancy (p = 0.002) were predictors of postoperative hypocalcemia. In multivariate analysis only parathyroid hormone in postoperative (p = 0.02) was associated with post-total thyroidectomy hypocalcemia. Conclusion: Preoperative serum concentrations of 25(OH) vitamin D were not predictors for post-total thyroidectomy hypocalcemia, whereas postoperative parathyroid hormone influenced the occurrence of this complication.-
Idioma: dc.languageen-
Idioma: dc.languagept_BR-
Relação: dc.relationBrazilian Journal of Otorhinolaryngology-
Direitos: dc.rightsopenAccess-
Palavras-chave: dc.subjectParathyroid hormone-
Palavras-chave: dc.subjectThyroidectomy-
Palavras-chave: dc.subjectVitamin D-
Título: dc.titlePreoperative vitamin D level as a post-total thyroidectomy hypocalcemia predictor: a prospective study-
Título: dc.titleNível pré-operatório de vitamina D como preditor de hipocalcemia pós-tireoidectomia total: estudo prospectivo-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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