Reduced graphene oxide decorated with AuNPs as a new aptamer-based biosensor for the detection of androgen receptor from prostate cells

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorCrulhas, Bruno P.-
Autor(es): dc.creatorBasso, Caroline R.-
Autor(es): dc.creatorParra, Joaõ P. R. L. L.-
Autor(es): dc.creatorCastro, Gustavo R.-
Autor(es): dc.creatorPedrosa, Valber A.-
Data de aceite: dc.date.accessioned2021-03-11T01:33:54Z-
Data de disponibilização: dc.date.available2021-03-11T01:33:54Z-
Data de envio: dc.date.issued2019-10-06-
Data de envio: dc.date.issued2019-10-06-
Data de envio: dc.date.issued2019-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1155/2019/5805609-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/187858-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/187858-
Descrição: dc.descriptionHere we described an aptasensor based on graphene oxide (GO) decorated with gold nanoparticles (AuNPs) able to detect the AR released by prostate cells, in order to provide new insights about the relationship between AR and prostate cancer for a more precise diagnosis for cancer. Characterization of the surface modified GE was carried out by cyclic voltammetry and electrochemical impedance spectroscopy using ferrocene as a redox probe. Under the optimized experimental conditions, a detection limit of 0.5 ng/mL (3σ/slope) was obtained by the present electrochemical biosensor, along with a linear range of 0-110 ng/mL. By virtue of excellent sensitivity, specificity, and repeatability, the present electrochemical biosensor provides a potential application in clinical diagnosis.-
Idioma: dc.languageen-
Relação: dc.relationJournal of Sensors-
Direitos: dc.rightsopenAccess-
Título: dc.titleReduced graphene oxide decorated with AuNPs as a new aptamer-based biosensor for the detection of androgen receptor from prostate cells-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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