SYNTHESIS; CHARACTERIZATION AND CYTOTOXIC ACTIVITY EVALUATION OF CYCLOPALLADATED COMPOUNDS CONTAINING ORTHOMETALLATED BENZALDEHYDEOXIME AND ETHYLENETHIOUREA AS LIGANDS

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorThomazella, Nothalia A.-
Autor(es): dc.creatorLemos, Sahra C.-
Autor(es): dc.creatorSouza, Ronan F. F. de-
Autor(es): dc.creatorSouza, Rodrigo A. de-
Autor(es): dc.creatorMauro, Antonio E.-
Autor(es): dc.creatorCarlos, Iracilda Z.-
Autor(es): dc.creatorNetto, Adelino V. G.-
Data de aceite: dc.date.accessioned2021-03-11T01:14:21Z-
Data de disponibilização: dc.date.available2021-03-11T01:14:21Z-
Data de envio: dc.date.issued2019-10-04-
Data de envio: dc.date.issued2019-10-04-
Data de envio: dc.date.issued2018-12-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.21577/0100-4042.20170293-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/185128-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/185128-
Descrição: dc.descriptionThe halide bridge cleavage reaction of the [Pd(C-2,N-bzox)(mu-Cl)](2). compound (bzox = benzaldehydeoxime) with ethylenethiourea (L) in the 1:2 molar ratio at room temperature yielded the cyclopalladated compound [Pd(C-2,N-bzox)(Cl)(L)] (1) whose replacement of the halide group by the addition of suitable salts afforded compounds of general formulae [Pd((C-2,N-bzox)(X)(L)] = {X = Br- (2), I-(3)}. All compounds were characterized by melting point, elemental analyses, infrared and H-1- and C-13{H-1}-NMR spectroscopies revealing the complexes formation with the oxime coordinated to Pd(II) as C,N-chelating and the ethylenethiourea as a monodentate ligand via the sulfur atom. Hie cytotoxicity of cyclopalladated compounds has been evaluated in vitro against murine mammary tumor cell (LM3) showing cytotoxic activity similar to cisplatin.-
Formato: dc.format1150-1155-
Idioma: dc.languagept_BR-
Publicador: dc.publisherSoc Brasileira Quimica-
Relação: dc.relationQuimica Nova-
Direitos: dc.rightsclosedAccess-
Palavras-chave: dc.subjectcyclopalladated complexes-
Palavras-chave: dc.subjectoximes-
Palavras-chave: dc.subjectethylenethiourea-
Palavras-chave: dc.subjectimidazolidine-2-thione-
Palavras-chave: dc.subjectcytotoxicity-
Título: dc.titleSYNTHESIS; CHARACTERIZATION AND CYTOTOXIC ACTIVITY EVALUATION OF CYCLOPALLADATED COMPOUNDS CONTAINING ORTHOMETALLATED BENZALDEHYDEOXIME AND ETHYLENETHIOUREA AS LIGANDS-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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