Recent advances in DNA vaccines for autoimmune diseases

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorSilva, Celio L.-
Autor(es): dc.creatorBonato, Vania L. D.-
Autor(es): dc.creatordos Santos-Junior, Rubens R.-
Autor(es): dc.creatorZarate-Blades, Carlos R.-
Autor(es): dc.creatorSartori, Alexandrina-
Data de aceite: dc.date.accessioned2021-03-10T17:11:28Z-
Data de disponibilização: dc.date.available2021-03-10T17:11:28Z-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2009-02-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1586/14760584.8.2.239-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/18254-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/18254-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionVaccination is one of the most powerful health tools available owing to its ability to confer protection against various diseases. The long-term impact of such protection in terms of public-health savings is nearly incalculable and becomes even more evident when considering if the vaccination concept is extended to the therapeutic potential of a given molecule. In this sense, DNA vaccines are especially important tools with enormous potential owing to the molecular precision that they offer. The properties of the plasmid DNA molecule in terms of stability, cost-effectiveness and lack of cold-chain requirement are additional advantages over traditional vaccines and therapeutics. We focus on the current knowledge of autoimmune mechanisms, engineering of DNA vaccines and attempts that have already been made in order to intervene in autoimmune processes. Our experience with a genetic vaccine containing the heat-shock protein gene (hsp65) from mycobacteria is also described.-
Formato: dc.format239-252-
Idioma: dc.languageen-
Publicador: dc.publisherExpert Reviews-
Relação: dc.relationExpert Review of Vaccines-
Relação: dc.relation4.271-
Relação: dc.relation1,551-
Direitos: dc.rightsclosedAccess-
Palavras-chave: dc.subjectautoimmunity-
Palavras-chave: dc.subjectDNA vaccine-
Palavras-chave: dc.subjecttolerance-
Palavras-chave: dc.subjectTreg cell-
Título: dc.titleRecent advances in DNA vaccines for autoimmune diseases-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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